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José Manuel Baselga (1959–2021)


José Manuel Baselga, renowned oncologist, died on 21 March at the age of 61 at his home in La Cerdanya, a beautiful Catalan county surrounded by the Spanish and French Pyrenees. Possibly the greatest drug developer of the past two decades, José was famous for, in his own words, “going to places and changing things.” Throughout his career, he transformed oncology practice and made the development of new treatments his mission.
Born in Barcelona, Spain, on 3 July 1959, José was raised close to the Vall d Hebron Hospital, an institution on which he would later leave his mark. He graduated from Universitat Autònoma de Barcelona in 1982 with an MD and then fulfilled his military service duty before starting his residency at the Vall d Hebron Hospital in 1985. With a year left in his residency, José moved to the United States to work at Kings County Hospital in Brooklyn, New York. According to his sister Eulalia, he lived in a modest apartment with windows that would not cl ....

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Nuvalent Presents Preclinical Data Demonstrating That ROS1 Inhibitor NUV-520 and ALK Inhibitor NUV-655 are Selective, Brain-Penetrant, and Active Against Drug-Resistance Mutations


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CAMBRIDGE, Mass., April 10, 2021 /PRNewswire/ Nuvalent, Inc., a biotechnology company creating precisely targeted therapies for clinically proven kinase targets in cancer, today announced preclinical data supporting advancement of its parallel lead programs in non-small cell lung cancer (NSCLC), including NUV-520 – a potential best-in-class ROS1-selective inhibitor – and NUV-655 – an ALK-selective inhibitor. Data are being presented at the 2021 American Association for Cancer Research (AACR) Virtual Annual Meeting from April 10-15 in two separate poster presentations. Posters will be archived on the Nuvalent website at www.nuvalent.com.
In addition, Nuvalent announces the appointment of leading medical oncologist Alexander Drilon, M.D., to its Scientific Advisory Board (SAB). Dr. Drilon currently serves as Chief of the Early Drug Development Service at Memorial Sloan Kettering Cancer Center (MSK) and brings deep expertise i ....

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MSK News: Taking Aim at Lung Cancer | Memorial Sloan Kettering Cancer Center


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Medical oncologist Alexander Drilon is leading the development of new targeted drugs that can control lung cancer better than ever before.
Middle school chorus and orchestra teacher Melissa Crouse had lived in the Pittsburgh area her whole life. But on a trip to visit her brother in southwest Florida, she decided on a whim to apply for teaching jobs there. The single mom, then 51, quickly received an offer.
“Three big things happened to me at the same time,” Melissa says. “I moved, I started a new job, and, after getting a physical for my new job, I was diagnosed with stage II lung cancer.” ....

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