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U S Food and Drug Administration Approves Augtyro™ (repotrectinib), a Next-Generation Tyrosine Kinase Inhibitor (TKI), for the Treatment of Patients with NTRK-Positive Locally Advanced or Metastatic Solid Tumors

U S Food and Drug Administration Approves Augtyro™ (repotrectinib), a Next-Generation Tyrosine Kinase Inhibitor (TKI), for the Treatment of Patients with NTRK-Positive Locally Advanced or Metastatic Solid Tumors
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Susan spinosaAlexander drilonNick botwoodBristol myers squibbNational cancer instituteDrug administrationExchange commissionBristol myers squibb companyEuropean society for medical oncologyEarly drug development serviceMemorial sloan kettering cancerImportant safety informationMedical oncologyBristol myersBlinded independent central reviewResponse evaluation criteria

U S Food and Drug Administration Approves Augtyrotm (repotrectinib), a Next-Generation Tyrosine Kinase Inhibitor (TKI), for the Treatment of Patients with NTRK-Positive Locally Advanced or Metastatic Solid Tumors

Bristol Myers Squibb today announced that the U.S. Food and Drug Administration (FDA) has granted accelerated approval of Augtyrotm (repotrectinib) for the treatment of adult and pediatric patients 12 years of age and older with solid tumors that.

Bristol myers squibbNick botwoodAlexander drilonSusan spinosaDrug administration approves augtyrotmNational cancer instituteBristol myers squibb companyExchange commissionProduct serviceEuropean society for medical oncologyDrug administrationNext generation tyrosine kinase inhibitorPositive locally advancedMetastatic solidMyers squibbEarly drug development service

Dr Jhaveri on the Implications of Treatment With RLY-2608 in Advanced ER+ Breast Cancer

Komal Jhaveri, MD, FACP, discusses the implications of investigating treatment with RLY-2608 in patients with PIK3CA-mutant advanced ER+ breast cancer.

Komal jhaveriJames cayneEndocrine therapy research programMemorial sloan kettering cancer centerEarly drug development serviceJames cayne chairJunior faculty

Dato-DXd May Be Better Tolerated Than Chemo in HR+/HER2– Breast Cancer

Dato-DXd May Be Better Tolerated Than Chemo in HR+/HER2– Breast Cancer
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United statesNew yorkJames cayneKomal jhaveriEndocrine therapy research programEuropean society for medical oncologyEarly drug development serviceAmerican cancer societyBreast cancer annual congressMedical oncologyBreast cancer annualJames cayne chairJunior facultyMemorial sloan kettering cancer center

Dato-DXd Reduces High-Grade TRAEs vs Chemo in Pretreated, HR+/HER2– Advanced Breast Cancer

Datopotamab deruxtecan was associated with lower rates of high-grade TRAEs vs chemotherapy in the phase 3 TROPION-Breast01 trial.

James cayneKomal jhaveriEarly drug development serviceEndocrine therapy research programBreast cancer congressCancer congressJames cayne chairJunior facultyMemorial sloan kettering cancer center