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ASCO 2021 recap: Lynparza s lift, Grail goes on, LAG validation & more

MedCity News ASCO 2021 recap: Lynparza’s lift, Grail goes on, LAG validation & more The American Society of Clinical Oncology’ annual meeting featured news highlights from the Merck, Novartis, and other drug giants. Meanwhile, some small biotechs rode the coattails of their larger counterparts and others forged their own paths with promising early results for new cancer drug targets. Shares0   The annual meeting of the America Society of Clinical Oncology came and went, and for the second year in a row, the pandemic meant that the cancer gathering was an all-digital affair. Big pharmaceutical companies grabbed most of the headlines with data supporting further development of some clinical candidates and in at least one case, potential expanded use of a blockbuster cancer drug as an earlier treatment. Targeted therapies have been gaining steam and this year’s conference saw the unveiling of data validating some new targets. Here’s a look back at some of the highlights

New treatment may improve outcomes for patients with BRCA mutation-associated early breast cancer

New treatment may improve outcomes for patients with BRCA mutation-associated early breast cancer Results were released this week on a new treatment with the potential to improve the outcomes for patients with hereditary BRCA mutations and high-risk, early-stage breast cancer. These results represent the first time a drug that blocks cancer cells from repairing their DNA (called a PARP inhibitor) has been shown to significantly reduce the risk of breast cancer returning in high-risk patients following completion of standard chemotherapy, surgery and radiation therapy. Titled Adjuvant Olaparib for Patients with BRCA1 or BRCA2 Mutated Breast Cancer, the paper appears in the June 3 issue of the

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