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Pear Announces Ohio Department of Mental Health and Addiction Services will Provide Access to Prescription Digital Therapeutics to Help Local Communities Continue Fight Against Opioid Addiction

Pear Announces Ohio Department of Mental Health and Addiction Services will Provide Access to Prescription Digital Therapeutics to Help Local Communities Continue Fight Against Opioid Addiction
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POT1 gene linked to glioma development mediates its effects in a sex-specific manner


POT1 gene linked to glioma development mediates its effects in a sex-specific manner
Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner.
Researchers found that female mice with glioma that lacked the gene survived less than males. This led them to investigate human glioma cells, where they found that low POT1 expression correlated with reduced survival in females.
Published in the journal
Cancer Research, the study also shows that, compared to males , female tumors had reduced expression of immune signatures and increased expression of cell replication markers, suggesting that the immune response and tumor cell proliferation seemed to be involved in favoring tumor growth. ....

Benjamin Deneen , Mariank Blattner , Ali Jalali , Melissa Bondy , Emily Henderson , Cancer Research , Stanford University , Researchers At Baylor College Of Medicine , Baylor College Of Medicine , Baylor College , Study First Author , Assistant Professor , Animal Model , Brain Tumor , Cell Proliferation , Immune Response , Ouse Model , பெஞ்சமின் டேனின் , அலி ஜலாலி , மெலிசா பாண்டி , எமிலி ஹென்டர்சன் , புற்றுநோய் ஆராய்ச்சி , ஸ்டான்போர்ட் பல்கலைக்கழகம் , ஆராய்ச்சியாளர்கள் இல் பேலர் கல்லூரி ஆஃப் மருந்து , பேலர் கல்லூரி ஆஃப் மருந்து , பேலர் கல்லூரி ,

POT1 gene mutation predisposes to glioma and affects survival in a sex-specific manner


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Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner. Researchers found that female mice with glioma that lacked the gene survived less than males. This led them to investigate human glioma cells, where they found that low POT1 expression correlated with reduced survival in females.
Published in the journal
Cancer Research, the study also shows that, compared to males , female tumors had reduced expression of immune signatures and increased expression of cell replication markers, suggesting that the immune response and tumor cell proliferation seemed to be involved in favoring tumor growth. ....

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