1 Abstract The devastating Ebola outbreak in West Africa in 2013-2016 accelerated the progress of several medical countermeasures (MCMs) against Ebola virus disease (EVD). Several IPs were used during that outbreak, but no conclusion on efficacy could be drawn. Only the Randomized Controlled Trial (RCT) on ZMapp was promising but inconclusive. More recently, during the second largest Ebola outbreak in North Kivu and Ituri provinces, Democratic Republic of the Congo (DRC), four IPs (Remdesivir, Regeneron, ZMapp and MAb114) have been evaluated in a RCT, the Pamoja Tulinde Maisha (PALM) study. Two products (Regeneron and MAb114) demonstrated efficacy as compared to the control arm, ZMapp. Very few side effects have been reported. Results from this scientifically sound study led the FDA to license both products, representing a milestone in EVD therapeutic field. These products can be produced relatively inexpensively and can be stockpiled. The administration of mAbs on EVD patients appears
In Mongolia, melting ice is revealing hidden archaeological treasures scroll.in - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from scroll.in Daily Mail and Mail on Sunday newspapers.
For many people who contract mild, moderate, or severe COVID-19, the disease s effects don t disappear when the infection fades. A systematic review and meta-analysis published Monday to the journal Scientific
Melting Mongolian ice reveals fragile artifacts that provide clues about how past people lived downtoearth.org.in - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from downtoearth.org.in Daily Mail and Mail on Sunday newspapers.
From the high Yukon to the mountains of Central Asia, melting ice exposes fragile ancient artifacts that tell the story of the past – and provide hints about how to respond to a changing climate.