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Armed with robots and 12,000 molecules, Scripps scientists hunt for the next COVID-19 drug

Researchers stress that developing new, improved treatments will be an important piece of our ongoing battle against the coronavirus ....

United States , Arnab Chatterjee , Scripps Research , Nature Medicine , New England Journal , Covid 19 , Sars Cov 2 , San Diego , ஒன்றுபட்டது மாநிலங்களில் , அர்னாப் சாட்டர்ஜி , ஸ்கிரிப்ட்கள் ஆராய்ச்சி , இயற்கை மருந்து , புதியது இங்கிலாந்து இதழ் , சான் டியாகோ ,

Known pharmaceutical compounds could provide new therapies for COVID-19

After screening over 12,000 existing treatments, researchers have found many promising antiviral compounds that could treat COVID-19. ....

Arnab Chatterjee , Thomas Rogers , Peter Schultz , Scripps Research , Nature Communications , National Institutes Of Health , Melinda Gates Foundation , Department Of Immunology , National Institutes , Coronavirus Disease Covid 19 , Ars Cov 2 , அர்னாப் சாட்டர்ஜி , தாமஸ் ரோஜர்ஸ் , பீட்டர் ஶுல்ட்ஸ் , ஸ்கிரிப்ட்கள் ஆராய்ச்சி , இயற்கை தகவல்தொடர்புகள் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , மெலிண்டா வாயில்கள் அடித்தளம் , துறை ஆஃப் நோயெதிர்ப்பு , தேசிய நிறுவனங்கள் ,

Extensive study identifies over a dozen existing drugs as potential COVID-19 therapies

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IMAGE: A researcher at Calibr, the drug discovery division of Scripps Research, working in the high-throughput screening facility used to identify potential COVID-19 therapies.
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Credit: Scripps Research
June 3, 2021 - LA JOLLA, CA Mining the world s most comprehensive drug repurposing collection for COVID-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that s driving the ongoing global pandemic.
Among those compounds, the Scripps Research study identified four clinically approved drugs and nine compounds in other stages of development with strong potential to be repurposed as oral drugs for COVID-19, according to results published June 3 in the journal ....

San Diego , United States , Amanda Roberts , Nathan Beutler , Thomas Rogers , James Ricketts , Mara Parren , Laura Riva , Peiting Kuo , Linlin Yang , Kastin Pan , Namir Shaabani , Karen Wolff , Peter Schultz , Elijah Garcia , Debashis Sahoo , John Teijaro , Emily Chen , Arnab Chatterjee , Edward Huang , Pradipta Ghosh , Malina Bakowski , Natalia Vargas , Soumita Das , Tu Trinhh Nguyen , Sean Joseph ,

Scientists identify many existing drugs with antiviral activity against coronavirus

Mining the world's most comprehensive drug repurposing collection for COVID-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that's driving the ongoing global pandemic. ....

Arnab Chatterjee , Malina Bakowski , Thomas Rogers , Peter Schultz , Emily Henderson , Scripps Research , Nature Communications , Melinda Gates Foundation , Department Of Immunology , Drug Discovery , Drug Repurposing , High Throughput Screening , Ars Cov 2 , அர்னாப் சாட்டர்ஜி , மாலினா பகோவ்ஸ்கி , தாமஸ் ரோஜர்ஸ் , பீட்டர் ஶுல்ட்ஸ் , எமிலி ஹென்டர்சன் , ஸ்கிரிப்ட்கள் ஆராய்ச்சி , இயற்கை தகவல்தொடர்புகள் , மெலிண்டா வாயில்கள் அடித்தளம் , துறை ஆஃப் நோயெதிர்ப்பு ,

Drug Repurposing for COVID-19: What Went Wrong?

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So far in the pandemic, support for research on drug repurposing particularly for inexpensive generics has not played a huge role in finding new treatments for COVID-19, but that appears to be changing.
Critics charge that drug repurposing is like looking for a needle in a haystack. It does not always work, and can raise false hopes and waste resources. In a March 7 interview with
60 Minutes, for instance, NIH director Francis Collins, MD, PhD, said drug repurposing is only going to work if you re kind of lucky, because you re basically picking things that were developed for a different disease. ....

University Of Pennsylvania , United States , Arnab Chatterjee , Francis Collins , David Fajgenbaum , Eli Lilly , Veronica Hackethal , Rena Conti , Armand Balboni , National Center , Harvard Medical School , Translational Sciences , California Institute For Biomedical Research Calibr , Us Army , Questrom School Of Business At Boston University , Institute For Health System Innovation , Overlooked Repurposing , Health System Innovation , Questrom School , Advancing Translational Sciences , California Institute , Biomedical Research , Focused Rescue , Accelerated Medchem , New Agents , Appili Therapeutics ,