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Scientists atSt. JudeChildren’s Research Hospital are working with colleagues in China to develop better therapy for childhood acute lymphoblastic leukemia (ALL). Results from a large phase 3 noninferiority clinical trial definitively showed that vincristine and dexamethasone pulses can be eliminated in patients with low-risk disease. The findings were published today in
The
Lancet Oncology.
Adding the chemotherapy vincristine plus a steroid (originally prednisone, and later dexamethasone) as pulse therapy for childhood ALL has been part of standard care since the 1970s. This is despite their being associated with neuropsychological side effects, neuropathy and other late effects. However, to date studies about the need for prolonged treatment with pulse therapy have been inconclusive. ....

Hong Kong , Hua Jiang , University Of Hong Kong , Hong Kong General , Hui Jiang , Hui Zhang , Jing Chen , Jingyan Tang , Aiguo Liu , Ju Gao , Yingchi Zhang , Wenyu Yang , Changda Liang , Minghua Yang , Kaili Pan , Runming Jin , Yongjun Fang , Chunfu Li , Yiping Zhu , Lirong Sun , Junj Yang , Jiaoyang Cai , Jie Yu , Xuedong Wu , Xiaowen Zhai , Ningling Wang ,

International collaboration helps refine treatment for childhood leukemia

International collaboration helps refine treatment for childhood leukemia
prnewswire.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from prnewswire.com Daily Mail and Mail on Sunday newspapers.

Hong Kong , Hua Jiang , University Of Hong Kong , Hong Kong General , Hui Jiang , Hui Zhang , Jing Chen , Jingyan Tang , Aiguo Liu , Ju Gao , Yingchi Zhang , Wenyu Yang , Changda Liang , Minghua Yang , Kaili Pan , Runming Jin , Yongjun Fang , Chunfu Li , Yiping Zhu , Lirong Sun , Junj Yang , Jiaoyang Cai , Jie Yu , Xuedong Wu , Xiaowen Zhai , Ningling Wang ,

Effects of a silage diet on the gut bacteria of horses explored in study


Horsetalk.co.nz
Effects of a silage diet on the gut bacteria of horses explored in study
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The Lachnospiraceae family was statistically more abundant in horses fed hay, researchers said, while it was the least abundant in horses fed silage. (File image)
The abundance of a key bacterial family that inhabits the equine gut fell away significantly in horses fed silage, when compared to those given hay or grass, researchers found.
The decline seen in the abundance of
Lachnospiraceae in horses fed silage was a significant finding, according to the researchers, as it may indicate inflammatory changes, as revealed by previous studies on humans. ....

Liang Deng , Jing Li , Yiping Zhu , Shulei Chen , Chunyan Zhu , Xuefan Wang , Veterinary Medicine At Shenyang Agricultural University , College Of Animal Husbandry , China Agricultural University , Shanghai Center , College Of Veterinary Medicine , Guanzhong Stud , Veterinary Medicine , Animal Husbandry , Shenyang Agricultural University , Agri Products Quality , Pasture Grass , Hay Diet , Equine Fecal , Creative Commons License , ஜிங் லி , ஷாங்காய் மையம் , கல்லூரி ஆஃப் கால்நடை மருந்து , கால்நடை மருந்து , விலங்கு வளர்ப்பு , வைக்கோல் உணவு ,