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Two copies of APOE4 may be more than just a risk factor for AD; the pair may cause the disease in 15%-20% of cases.

San franciscoUnited statesUnited kingdomComunidad autonoma de catalunaDavid curtisYuko haraSant pauJuan forteaPaul mathewsYadong huangReisa sperlingMemory unit of the neurology departmentUniversity of californiaAlzheimer researchAlzheimer drug discovery foundationGenetics institute at university of college london