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US scientists link mitochondrial DNA levels with severity of COVID-19


US scientists link mitochondrial DNA levels with severity of COVID-19
21 January 2021 | News
Mitochondrial DNA levels were much higher in patients who eventually were admitted to the ICU, intubated or died
Source: Shutterstock
Scientists at Washington University School of Medicine in St Louis have shown that a relatively simple and rapid blood test can predict within a day of a hospital admission which patients with COVID-19 are at highest risk of severe complications or death.
The study, published Jan 14 in JCI Insight, involved nearly 100 patients newly admitted to the hospital with COVID-19.
The blood test measures levels of mitochondrial DNA, a unique type of DNA molecule that normally resides inside the energy factories of cells. ....

Hrishikeshs Kulkarni , Williame Maritz , Andrewe Gelman , Scientists At Washington University School Of Medicine , Drug Administration , Department Of Surgery , Washington University School , Williame Maritz Endowed Chair , Assistant Professor , Rapid Blood Test , Covid 19 , Mitochondrial Dna , Washington University School Of Medicine , St Louis , விஞ்ஞானிகள் இல் வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , துறை ஆஃப் அறுவை சிகிச்சை , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி , உதவியாளர் ப்ரொஃபெஸர் , விரைவான இரத்தம் சோதனை , மைட்டோகாண்ட்ரியல் டீயெநே , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , ஸ்டம்ப் லூயிஸ் ,

Rapid Blood Test Identifies COVID-19 Patients at High Risk of Severe Disease


 
Pictured are damaged mitochondria (dark grey areas) released from human lungs. The small dark dots surrounding the mitochondria are magnetic beads that carry antibodies used to isolate and study unhealthy mitochondria that have been released from dying tissues. Credit: Wandy Beatty
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One of the most vexing aspects of the COVID-19 pandemic is doctors inability to predict which newly hospitalized patients will go on to develop severe disease, including complications that require the insertion of a breathing tube, kidney dialysis or other intensive care. Knowledge of a patient s age and underlying medical conditions can help predict such outcomes, but there are still surprises when younger, seemingly healthier patients suffer severe complications that can lead to death. ....

Jane Ohalloran , Phillip Mudd , Davide Scozzi , Hrishikeshs Kulkarni , Williame Maritz , Charles Goss , Andrewe Gelman , School Of Medicine , Drug Administration , Washington University School Of Medicine , Department Of Surgery , Washington University School , Endowed Chair , Marlene Cano , Barnes Jewish Hospital , Janeo Halloran , ஜேன் ஓஹள்லோரன் , பிலிப் சேறு , சார்லஸ் காஸ் , பள்ளி ஆஃப் மருந்து , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , துறை ஆஃப் அறுவை சிகிச்சை , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி , வழங்கப்பட்டது நாற்காலி , மார்லின் கேனோ , களஞ்சியங்கள் நகை மருத்துவமனை ,

Rapid blood test identifies COVID-19 patients at high risk of severe disease | The Source


Measuring mitochondrial DNA could predict who will need ICU care, intubation
January 15, 2021
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A new study from Washington University School of Medicine in St. Louis suggests that measuring mitochondrial DNA in the blood of patients with COVID-19 can help predict which patients are at highest risk of severe disease, requiring more intensive care. Mitochondrial DNA levels are a measure of tissue damage. Pictured are damaged mitochondria (dark grey areas) released from human lungs. The small dark dots surrounding the mitochondria are magnetic beads that carry antibodies used to isolate and study unhealthy mitochondria that have been released from dying tissues. (Image: Wandy Beatty) ....

Jane Ohalloran , Phillip Mudd , Davide Scozzi , Hrishikeshs Kulkarni , Williame Maritz , Charles Goss , Andrewe Gelman , Children Discovery Institute , School Of Medicine , National Center , Washington University Institute Of Clinical , National Institutes Of Health , Drug Administration , Washington University School Of Medicine , Department Of Surgery , Translational Sciences , Barnes Jewish Hospital Foundation , Research Program , Washington University School , Endowed Chair , Marlene Cano , Barnes Jewish Hospital , Janeo Halloran , Discovery Institute , National Institutes , Washington University Institute ,

New Blood Test Predicts COVID-9 Recovery


New Blood Test Predicts COVID-9 Recovery
by Karishma Abhishek on 
January 17, 2021 at 6:27 PM
Developing
sudden failure of organs that leads to various complications like respiratory or kidney inefficiency or requiring other intensive care remains one of the
challenging aspects of COVID-19 that may cause death even in young patients.
With an aim to explore which hospitalized patients can get into such complications, involving nearly 100 patients newly admitted to the hospital with COVID-19, a simple and rapid blood test has been formulated by scientists at Washington University School of Medicine in St. Louis.
Within a day of a hospital admission, this blood test can predict the risk of patients with COVID-19 who are highly prone to develop severe complications or death, published in the journal JCI Insight. ....

Williame Maritz , Andrewe Gelman , Grouptorsion Testisorchidectomy , Drug Administration , Bombay Blood Group , Washington University School Of Medicine , Department Of Surgery , Washington University School , Rapid Blood Test , Endowed Chair , Risk Factors Contribute , Breath Count Calculator , Itself Lead , Undescended Testiclesvaricocelequiz , Depressiontesticle Pain , Evaluationbombay Blood Grouptorsion , Covid 19 , New Rapid Blood Test , Inflammatory Markers , Cell Death , Organ Failures , Mitochondrial Dna , குண்டு இரத்தம் குழு , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , துறை ஆஃப் அறுவை சிகிச்சை , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ,