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Having an unhealthy heart could lead to a higher risk of being diagnosed with COVID-19


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People with unhealthy heart structures and poorer functioning hearts have a significantly higher risk of being diagnosed with COVID-19 infection, according to research by Queen Mary University of London, in collaboration with the Medical Research Council Lifecourse Epidemiology Unit (The University of Southampton).
The researchers made use of the comprehensive and internationally unique UK Biobank database, which includes health and genetic information from over half a million participants from across the UK, including detailed magnetic resonance imaging (MRI) of their hearts as well as linkages to COVID-19 test results from Public Health England.
The team investigated records from 310 Biobank participants to see whether pre-existing features of the heart anatomy and function, as demonstrated on heart MRI scans, were linked to having a positive COVID-19 test result. ....

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Significant gender disparities revealed in COVID-19 clinical trial leadership


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Less than one-third of COVID-19 clinical trials are led by women, which is half the proportion observed in non-COVID-19 trials, according to research led by Queen Mary University of London, University of St Andrews, Brigham and Women s Hospital and Harvard Medical School.
The study suggests that gender disparities during the pandemic may signify not only a lack of women s leadership in international clinical trials and new research projects, but also may expose the imbalances in women s access to research activities and funding during health emergencies.
The results of the study are being publicised to mark International Women s Day on Monday 8 March. This year s theme is Choose To Challenge which aims to encourage people to challenge and call out gender bias and inequality. ....

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Secrets of sealed 17th century letters revealed by dental X-ray scanners


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VIDEO: Computer-generated unfolding animation of sealed letter DB-1538. In our paper we describe how virtual unfolding was used to read the contents of sealed letterpackets from 17th-century Europe without physically opening.
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Credit: Courtesy of the Unlocking History Research Group archive.
In a world first, an international team of researchers has read an unopened letter from Renaissance Europe - without breaking its seal or damaging it in any way.
The research, published in
Nature Communications, describes how an X-ray scanner used in dental research and virtual unfolding allowed the interdisciplinary team to read the contents of a securely and intricately folded letter which has remained unopened for 300 years, while preserving its valuable physical evidence. ....

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