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New class of drug leads to 30% reduced risk of death for bladder cancer patients

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A new type of drug that helps target chemotherapy directly to cancer cells has been found to significantly increase survival of patients with the most common form of bladder cancer, according to results from a phase III clinical trial led in the UK by Queen Mary University of London and Barts Health NHS Trust.
The results are published in the
New England Journal of Medicine and were presented at the 2021 American Society of Clinical Oncology s Genitourinary Cancers Symposium.
Urothelial cancer is the most common type of bladder cancer (90 percent of cases) and can also be found in the renal pelvis (where urine collects inside the kidney), ureter (tube that connects the kidneys to the bladder) and urethra. Globally, approximately 549,000 new cases of bladder cancer and 200,000 deaths are reported annually. ....

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Consuming omega-3 fatty acids could prevent asthma

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New research suggests that a higher dietary intake of long chain omega-3 fatty acids in childhood may reduce the risk of developing subsequent asthma, but only in children carrying a common gene variant. The study, led by Queen Mary University of London, is in collaboration with the University of Bristol and University of Southampton, UK, and Karolinska Institutet, Sweden.
In the UK, 1.1 million children (1 in 11) are currently receiving treatment for asthma and most adult asthma begins in childhood. The NHS spends around £1 billion a year treating and caring for people with asthma.
Senior author, Professor Seif Shaheen from Queen Mary University of London, said: Asthma is the most common chronic condition in childhood and we currently don t know how to prevent it. It is possible that a poor diet may increase the risk of developing asthma, but until now most studies have taken snap-shots , measuring diet and asthma over a short period of time. Instead, we m ....

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Patients of Asian and black backgrounds more likely to die from COVID, large study reveals

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Patients of Asian and black backgrounds suffered disproportionate rates of premature death from COVID-19, according to a study of 1,737 patients by Queen Mary University of London and Barts Health NHS Trust.
The study, published in
BMJ Open, is one of the most comprehensive studies exploring COVID-19 outcomes in black, Asian and minority ethnic populations so far reported, from one of the largest and most diverse UK hospital COVID-19 cohorts, representing a majority ethnically diverse population (only 35.2 per cent of patients identified as White ethnicity).
The work resulted from a new interdisciplinary collaboration between intensive care physicians and HIV physicians. The researchers looked at data from all patients aged 16 years or over with confirmed SARS-CoV-2 infection and admitted to the five acute hospitals within Barts Health NHS Trust, between 1 January and 13 May 2020. ....

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£6.7m to 'harness' the power of NHS patient data and develop targeted care

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Barts Life Sciences is harnessing the untapped resource of patient data to discover new ways of improving patient care.
Specific health data collected from Barts Health NHS Trust patients over the course of their care will be securely analysed as part of new research that will directly benefit the 2.5 million patients the Trust cares for, as well as patients across the UK and beyond.
The £6.7m investment by Barts Charity marks a significant commitment to deliver advanced disease prevention and treatment to a population with some of the highest rates of illness and disadvantage in the UK, and to support east London s growing life and health data sciences sector. ....

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