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How to extract RNA from hard-to-lyse samples in TRIzol

RNA isolation is a challenging procedure. Unlike DNA, which is highly stable, RNA is very unstable, quickly digested by RNase enzymes if their activity isn’t immediately inhibited. One popular reagent in RNA isolation protocols is TRIzol ® . TRIzol was specifically formulated to isolate total RNA from any sample type in the modern research laboratory, whether in academia or industry: cells, hard to ly ....

Zymo Research , Application Note , Rna Extraction , Rna Extraction , Zymo Research , Well Lysis ,

Proximity labeling to identify high-confidence SARS-CoV-2 interactors

A recent report published in the STAR Protocols journal depicted a protocol for an antibody-based proximity labeling to discover biotinylated interactors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ....

Coronavirus Disease Covid 19 , Ars Cov 2 , Binding Affinity , Well Lysis , Covid 19 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Western Blot ,

New Spex Genomax 2050 accelerates the extraction of molecules

Obtain fast and efficient extraction of nucleic acids, proteins, and other molecules with the new Spex® Genomax® 2050; a high-throughput plant and animal tissue homogenizer and cell lyser designed for rapid cell disruption, cell lysis and tissue homogenization through bead beating. ....

Spex Genomax , Image Credit , Purpose Clamp , Spex Genomic , Well Lysis ,

Could soluble CD24 offer some hope against severe COVID-19?

A recent randomized phase III trial conducted by researchers at the Ohio State University, Columbus, OH, US, evaluated the impact of CD24Fc in severe COVID-19 patients and showed promising clinical efficacy. This study is available as a preprint on the medRxiv server. ....

Susha Cheriyedath , Ohio State University , Immunological Insights Into , Therapeutic Roles , Against Severe , Image Credit , Acute Respiratory Distress Syndrome , Ngiotensin Converting Enzyme 2 , Well Lysis , Coronavirus Disease Covid 19 , Flow Cytometry , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,