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Researchers create an innovative tool for the reliable and efficient study of gene function

A team of scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) led by Rui Benedito has generated a novel genetic tool, called iSuRe-HadCre, that enables the induction of precise genetic alterations in whole tissues or in individual cells with high efficiency and reliability. This new technology is set to become an important tool in biomedical research that uses mouse models to modify and understand gene function. ....

Irene Garc , Investigaciones Cardiovasculares , Rui Benedito , Irene Garcia Gonzalez , Nucleic Acids Research , Nucleic Acids ,

Researchers reveal secrets of aging beta cells and their ability to secrete insulin

A new study reveals that aging human pancreatic beta cells display features of senescence while maintaining elevated levels of genes crucial for their function. Despite their aging status, these cells therefore exhibit an ability to release insulin in response to glucose, aiding in blood sugar regulation. ....

Ittai Ben Porath , Nucleic Acids Research , Faculty Of Medicine The Hebrew University , Milan Patra , Professors Ittai Ben Porath , Yuval Dor , Hebrew University , Nucleic Acids , Professor Ittai Ben ,

Unveiling the role of AGO's post-translational modifications in plant gene regulation

Unveiling the role of AGO's post-translational modifications in plant gene regulation
phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.

Andrea Mart , Antonela Lavatelli , Nucleic Acids Research , Agricultural Genomics , Nucleic Acids ,

Researchers uncover protein SRSF1's uncommon ability to bind and unfold RNA G-quadruplexes

Researchers uncover protein SRSF1's uncommon ability to bind and unfold RNA G-quadruplexes
phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.

Nucleic Acids Research , Birmingham Department , Chemistry Professor Jun Zhang , Naiduwadura Ivon Upekala De Silva , Nucleic Acids ,