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New study shows how the Crimean-Congo hemorrh

<p><strong>Researchers at Karolinska Institutet, in collaboration with JLP Health and others, have identified how the tick-borne Crimean-Congo haemorrhagic fever virus enters our cells. The results are published in <em>Nature Microbiology </em>and are an important step in the development of drugs against the deadly disease. </strong></p>
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United States , Nazif Elaldi , Ali Mirazimi , Stephanie Devignot , Volkerm Lauschke , Ahmed Ibrahim , Vanessam Monteil , Maxj Kellner , Georg Michlits , Davidw Hawman , Samir Abdurahman , Mattia Mirandola , Josephm Penninger , Friedemann Weber , Ioannis Pittarokoilis , Karolinska Institutet , Moritz Horn , Cristiano Salata , Heinz Feldmann , Nuria Monserrat , Binnur Bagci , Hyesoo Kwon , Sonia Youhanna , Sebastianw Platzer , Swedish Research Council , Helmholtz Centre For Infection Research ,

Ideas, Inventions And Innovations : Fast Twitch, Slow Twitch; 1 in 5 People Have Mutant Gene To Better Tolerate Cold Temperatures


Ideas, Inventions And Innovations
Fast Twitch, Slow Twitch; 1 in 5 People Have Mutant Gene To Better Tolerate Cold Temperatures
Almost one in five people lacks the protein α-actinin-3 in their muscle fibre. Researchers at Karolinska Institutet now show that more of the skeletal muscle of these individuals comprises slow-twitch muscle fibres, which are more durable and energy-efficient and provide better tolerance to low temperatures than fast-twitch muscle fibres. The results are published in The American Journal of Human Genetics.
Photo: Getty Images
Skeletal muscle comprises fast-twitch (white) fibres that fatigue quickly and slow-twitch (red) fibres that are more resistant to fatigue. The protein α-actinin-3, which is found only in fast-twitch fibres, is absent in almost 20 per cent of people – almost 1.5 billion individuals – due to a mutation in the gene that codes for it. In evolutionary terms, the presence of the mutated gene increased when humans m ....

United States , Karolinska Institutet , Tomas Venckunas , Harrisond Wood , Nerijus Eimantas , Marius Brazaitis , Maja Schlittler , Peterj Houweling , Niklas Ivarsson , Volkerm Lauschke , Volker Lauschke , Danielc Andersson , Henrikas Paulauskas , Australia National Health , Swedish Society For Medical Research , Department Of Physiology , Lithuanian Sports University In Kaunas , Lung Foundation , Swedish Research Council , Swedish National Centre For Research , University Of Melbourne , Research Council Of Lithuania , Research Council , American Journal , Lithuanian Sports University , Swedish National Centre ,