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New study shows how the Crimean-Congo hemorrh

<p><strong>Researchers at Karolinska Institutet, in collaboration with JLP Health and others, have identified how the tick-borne Crimean-Congo haemorrhagic fever virus enters our cells. The results are published in <em>Nature Microbiology </em>and are an important step in the development of drugs against the deadly disease. </strong></p>
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United States , Nazif Elaldi , Ali Mirazimi , Stephanie Devignot , Volkerm Lauschke , Ahmed Ibrahim , Vanessam Monteil , Maxj Kellner , Georg Michlits , Davidw Hawman , Samir Abdurahman , Mattia Mirandola , Josephm Penninger , Friedemann Weber , Ioannis Pittarokoilis , Karolinska Institutet , Moritz Horn , Cristiano Salata , Heinz Feldmann , Nuria Monserrat , Binnur Bagci , Hyesoo Kwon , Sonia Youhanna , Sebastianw Platzer , Swedish Research Council , Helmholtz Centre For Infection Research ,

Brain organoids uncover mechanisms of virus-induced microcephaly


Date Time
Brain organoids uncover mechanisms of virus-induced microcephaly
Human brain organoids stained for neural stem cells (magenta) and Zika virus (left, green) och Herpes Simplex Virus 1 (right, green).
Credits: Krenn/CellStemCell/IMBA
A study involving researchers at Karolinska Institutet and IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – demonstrates how zika and herpes viruses can lead to brain malformations during early pregnancy. The researchers used 3D models of human brains to study which mechanisms are involved in virus-induced microcephaly, a condition where babies are born with smaller-than-usual heads. The results are published in the journal Cell Stem Cell. ....

Julia Spanier , Karolinska Institutet , Thomas Burkard , Raissa Rilo , Patricia Garcez , Arianna Calistri , Krenn Cellstemcell , Veronica Krenn , Camilla Bosone , Ali Mirazimi , Ulrich Kalinke , Cristiano Salata , Martin Stenmark , European Union , Horizon Research , Department Of Laboratory Medicine , Herpes Simplex Virus , Professor Ali , Molecular Biotechnology , Austrian Academy , Cell Stem , Laboratory Medicine , ஜூலியா ஸ்பேனியர் , பாட்ரிசியா கர்செஜ் , ஐரோப்பிய தொழிற்சங்கம் , அடிவானம் ஆராய்ச்சி ,