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Worrying symptoms of silent killer that affects one in five and can't be treated

High levels Lp(a), a largely genetic form of cholesterol, can lead to heart attacks and strokes and currently because it is genetic, rather than lifestyle based - there is no treatment ....

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Bad cholesterol: New oral drug may lower levels of lipoprotein(a)

In a phase 1 clinical trial, the experimental drug muvalaplin successfully lowered the levels of a previously untreatable form of bad cholesterol, lipoprotein(a). ....

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Researchers Develop Pill to Rapidly Lower Bad Cholesterol Levels

The innovation marks the pioneering creation of an oral drug that specifically targets lipoprotein(a). ....

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Breakthrough Drug Targets a Form of "Bad Cholesterol"

A clinical trial has demonstrated the success of Muvalaplin, the first oral drug ever developed to target Lipoprotein(a), a largely genetic form of cholesterol that increases the risk of heart attack. ....

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World first drug to target form of previously

Simultaneous presentation at European Cardiology Conference and publication in JAMA will detail the world's first oral drug for the treatment of a type of high cholesterol - called Lp(a) - that is a potentially more dangerous version of the so called "bad" cholesterol, LDL, because it is stickier and may be more likely to cause blockages and blood clots in your arteries.

It is estimated that up to 20% of people worldwide have high levels of Lp(a), which is associated with a person's risk of experiencing a heart attack, strokes or other serious cardiac event. Importantly Lp(a) can be present even in younger adults and otherwise healthy people with no other known cardiovascular risks - and often remains undetected until a cardiac event has occurred. ....

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