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Microglial activation is critical for modulating the neuroinflammatory process and the pathological progression of neurodegenerative diseases, such as Alzheimer's disease (AD). Microglia are involved in forming barriers around extracellular neuritic plaques and the phagocytosis of β-amyloid peptide (Aβ). In this study, we tested the hypothesis that periodontal disease (PD) as a source of infection alters inflammatory activation and Aβ phagocytosis by the microglial cells. Experimental PD was induced using ligatures in C57BL/6 mice for 1, 10, 20, and 30 days to assess the progression of PD. Animals without ligatures were used as controls. Maxillary bone loss and local periodontal tissue inflammation associated with the development of PD were confirmed by morphometric bone analysis and cytokine expression, respectively. The frequency and the total number of activated microglia (CD45+ CD11b+ MHCII+) in the brain were analyzed by flow cytometry. Mouse m ....
Acute exposure to foodborne pathogens not sufficient to induce α-syn changes in healthy adult females; male sex, bowel disease, toxin, ageing to be present. ....
BioSFerA Project Presented at ECOS 2021 Conference – Advanced BioFuels USA advancedbiofuelsusa.info - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from advancedbiofuelsusa.info Daily Mail and Mail on Sunday newspapers.
Researchers from China looked at the anti-staphylococcal activities of berberine, an isoquinoline alkaloid derived from the traditional Chinese medicinal herb, Coptis chinensis, and evaluated its [.] ....
Flow cytometry to advance decontamination and sterilisation processes europeanpharmaceuticalreview.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from europeanpharmaceuticalreview.com Daily Mail and Mail on Sunday newspapers.