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Dr Anders on the Rationale For Investigating Tivumecirnon Plus Pembrolizumab in NSCLC

Robert A. Anders, MD, PhD, discusses the rationale for investigating the use of tivumecirnon in patients with non–small cell lung cancer, as well as interim data from the dose-expansion portion of the phase 1/2 FLX475-02 study of this agent alone and in combination with pembrolizumab.
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Roberta Anders , Johns Hopkins University School Of Medicine , Johns Hopkins Sidney Kimmel Cancer Center , Johns Hopkins University School , Patients With Non Small Cell Lung Cancer , Trop 2 Adcs ,

Dr Levy on the Ongoing Development of TROP-2 ADCs in NSCLC

Benjamin Philip Levy, MD, discusses the ongoing development of the TROP-2 directed antibody-drug conjugates sacituzumab govitecan-hziy and datopotamab deruxtecan in non–small cell lung cancer, their different toxicity profiles, as well as the potential categorization of emerging ADCs as onco-directed therapies in this patient population. ....

Johns Hopkins Sidney Kimmel Cancer Center , Johns Hopkins University School Of Medicine , Benjamin Philip Levy , Johns Hopkins University School , Medical Oncology , Sibley Memorial Hospital , Patients With Non Small Cell Lung Cancer , Johns Hopkins Sidney Kimmel Cancer Center At Sibley Memorial Hospital , Trop 2 Adcs ,