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CCR4 Antagonists May Bolster Immune Responses With Checkpoint Inhibitors in PD-L1+ NSCLC

The addition of tivumecirnon to pembrolizumab was safe, well-tolerated, and clinically active vs the historical activity of pembrolizumab monotherapy in patients with checkpoint inhibitor–naive non–small cell lung cancer. ....

United States , Johns Hopkins University , Roberta Anders , Johns Hopkins Kimmel Cancer Center , Johns Hopkins University School Of Medicine , Johns Hopkins University School , Non Small Cell Lung Cancer , Pd L1 ,

Dr Anders on the Rationale For Investigating Tivumecirnon Plus Pembrolizumab in NSCLC

Robert A. Anders, MD, PhD, discusses the rationale for investigating the use of tivumecirnon in patients with non–small cell lung cancer, as well as interim data from the dose-expansion portion of the phase 1/2 FLX475-02 study of this agent alone and in combination with pembrolizumab.
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Roberta Anders , Johns Hopkins University School Of Medicine , Johns Hopkins Sidney Kimmel Cancer Center , Johns Hopkins University School , Patients With Non Small Cell Lung Cancer , Trop 2 Adcs ,

New pathologic scoring system could help predict survival in lung cancer patients

A new pathologic scoring system that accurately assesses how much lung tumor is left after a patient receives presurgical cancer treatments can be used to predict survival, according to new research led by investigators at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center and the Mark Foundation Center for Advanced Genomics and Imaging at the Johns Hopkins University. ....

United Kingdom , San Diego , United States , France General , New Jersey , Johns Hopkins , Edward Gabrielson , Julie Stein Deutsch , Jaroslaw Jedrych , Lily Ramsey , Peter Illei , Elizabeth Thompson , Daphne Wang , Patrickm Forde , Roberta Anders , Ludmila Danilova , Janis Taube , Ashley Cimino Mathews , Bristol Myers Squibb , Johns Hopkins University , Johns Hopkins University School Of Medicine , Division Of Dermatopathology , Ono Pharmaceutical Company Ltd , Mark Foundation For Cancer Research , Society For Immunotherapy Of Cancer , Mark Foundation Center ,

Key to Unlocking Immunotherapy for Pancreatic Cancer Discovered

Key to Unlocking Immunotherapy for Pancreatic Cancer Discovered
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