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Alltrna Unveils $109M to Make tRNA a Universal Therapy for Genetic Diseases

Flagship Pioneering-founded Alltrna is developing tRNA therapies to address genetic diseases driven by truncated versions of proteins. By addressing an aberrant genetic instruction underpinning many diseases, the startup is developing what it describes as a potential “universal solution.” ....

United Kingdom , United States , Michelle Werner , Tevard Biosciences , American Society Of Cell , Bristol Myers Squibb , Massachusetts Based Alltrna , Flagship Pioneering , American Society , Weight Loss , Medical Devices , Healthcare Innovation , Medcity News , Medcity News , San Francisco , Life Sciences , Rock Health , Startup Advice , Startup Funding , Patient Monitoring System , Otion Sensors , Healthcare It , Foodborne Pathogens , Iagnostics Company , Iagnostic Platforms , Minimally Invasive Surgery ,

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

Researchers examined molecular-level differences in ribosomal translational fidelity between humans and bacteria. ....

Protein Data Bank , Amino Acid , Protein Synthesis , Ibonucleic Acid , Ignaling Pathway , Transfer Rna ,

Naturally produced molecule directly targets and keeps Fusobacteria under control

Researchers at the Forsyth Institute have discovered an important mechanism that may have profound implications for how we prevent colorectal cancer. Oddly enough, their discovery began in the mouth. ....

Wenyuan Shi , Mengdi Yang , Emily Henderson , Jiahe Li , Cancer Research Industry , Forsyth Institute , Cancer Research , Northeastern University , Chemical Modifications , Host Derived Transfer , Microbial Ecology , Forsyth Senior Member , Pu Ting Dong , Research Industry Focus , Lujia Cen , Colorectal Cancer , Public Health , Transfer Rna ,

New method for capturing moments during protein translation

Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like gene regulation has been greatly enhanced by the development of a process termed PETEOS short for peptidyl-tRNA enrichment using organic extraction and silica adsorption. ....

Aimee Molineux , Hideki Taguchi , Tokyo Institute Of Technology Tech , Nucleic Acids Research , Tokyo Institute Of Technology , Tokyo Tech , Image Credit , Tokyo Institute , Nucleic Acids , Industry Focus , E Coli , Ene Expression , Molecular Biology , Protein Synthesis , Transfer Rna ,

Chinese researchers discover new bacterial tRNA species-Xinhua

Chinese researchers discover new bacterial tRNA species- ....

Liu Guangxiu , Institute Of Eco , Nucleic Acids Research , Chinese Academy Of Sciences , Chinese Academy , Northwest Institute , Nucleic Acids , Transfer Rna ,