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Patchwork of Mutations Contribute to Bipolar Disorder

Patchwork of Mutations Contribute to Bipolar Disorder
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Japan General , Atsushi Takata , Mizuho Ishiwata , Takashi Hayama , Shinichi Kuriyama , Masaki Nishioka , Kumiko Fujii , Jun Takayama , Tadafumi Kato , Junko Ueda , Toshiyuki Someya , Gen Tamiya , Naomi Sakai , Statistical Genetics Team , Department Of Psychiatry , Department Of Molecular Pathology Mood Disorders , Department Of Integrative Genomics , Research Institute For Diseases Of Old Age , Laboratory For Molecular Dynamics Of Mental Disorders , Juntendo University Graduate School Of Medicine , Tohoku University School Of Medicine , Juntendo University , Tohoku University , Laboratory For Molecular Pathology Of Psychiatric Disorders , Shiga University Of Medical Science , Tohoku Medical Megabank Organization ,

Patchwork of mutations contributing to bipola

Bipolar disorder (BD) is a serious psychiatric disorder affecting around 1% of the population worldwide. While medications are indispensable for these patients, they are not completely effective, and the underlying genetic architecture and pathogenesis of BD remain unresolved. Researchers from Japan have now used deep exome sequencing to show that mosaic variants/mutations found in genes related to developmental disorders and autism spectrum disease and in the mitochondrial tRNA region could be associated with BD. ....

Japan General , Jun Takayama , Tadafumi Kato , Gen Tamiya , Mizuho Ishiwata , Atsushi Takata , Takashi Hayama , Naomi Sakai , Junko Ueda , Masaki Nishioka , Toshiyuki Someya , Shinichi Kuriyama , Kumiko Fujii , Department Of Molecular Epidemiology , Tohoku University School Of Medicine , Laboratory For Molecular Pathology Of Psychiatric Disorders , Department Of Integrative Genomics , Department Of Psychiatry , Juntendo University , Laboratory For Molecular Dynamics Of Mental Disorders , Shiga University Of Medical Science , Method Of Research , Juntendo University Graduate School Of Medicine , Department Of Preventive Medicine , Statistical Genetics Team , Tohoku Medical Megabank Organization ,

FDA Approves Rexulti For Agitation Associated With Dementia Due To Alzheimer's

The U.S. Food and Drug Administration announced the supplemental approval of Rexulti (brexpiprazole) oral tablets to treat agitation associated with dementia due to Alzheimer's disease. ....

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Otsuka Holdings Co., Ltd. (OTCMKTS:OTSKF) Sees Large Decline in Short Interest

Otsuka Holdings Co., Ltd. (OTCMKTS:OTSKF – Get Rating) was the target of a significant drop in short interest in April. As of April 30th, there was short interest totalling 254,700 shares, a drop of 44.8% from the April 15th total of 461,400 shares. Based on an average daily trading volume, of 400 shares, the days-to-cover […] ....

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Otsuka (OTCMKTS:OTSKF) Stock Price Down 3.8%

Otsuka Holdings Co., Ltd. (OTCMKTS:OTSKF – Get Rating) was down 3.8% on Monday . The company traded as low as $34.07 and last traded at $34.07. Approximately 500 shares changed hands during trading, a decline of 72% from the average daily volume of 1,760 shares. The stock had previously closed at $35.41. Otsuka Stock Performance […] ....

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