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Tumor mutations may not predict response to immuno

The number of mutations in the DNA of cancerous tumors may not be an indicator of how well patients will respond to immune checkpoint inhibitors (ICIs), a ....

United States , Zhao Zhu , Magdalena Espinoza , Maishara Muquith , Jakel Hamon , David Hsieh , Children Medical Center Research Institute , Leader Of The Development , Haroldc Simmons Comprehensive Cancer Center , Drug Administration , Division Of Hematology , Southwestern Medical Center , Research Institute Of Texas , Caris Precision Oncology Alliance , Simmons Cancer Center , Cancer Research Program , Therapeutic Oncology Research , Josephine Hughes Sterling Foundation , Nature Cancer , Assistant Professor , Internal Medicine , Comprehensive Cancer Center , Medical Center Research Institute , Clinical Assistant Professor , Distinguished Chair , Therapeutic Oncology ,

Combined therapy makes headway for liver cancer

A drug that targets a protein known as phosphatidylserine boosted the response rate for hepatocellular carcinoma (HCC) patients receiving immunotherapy without ....

United States , Yujin Hoshida , Eugenep Frenkel , Paula Calvert , Jay Lohrey , Radhika Kainthla , Chul Ahn , Jakel Hamon , Leticia Khosama , Amitg Singal , Peter Odonnell Jr , Ellen Siglinsky , Adamc Yopp , Heather Kline , Willisc Maddrey , David Hsieh , Zhao Zhu , Syedm Kazmi , Rolf Brekken , Courtney Katz , Mary Claire Maxwell , Research Institute Of Texas , Cancer Center Support Grant , Therapeutic Oncology Research , Simmons Cancer Center , Tissue Regeneration Program ,

Combined therapy makes headway for liver cancer

A drug that targets a protein known as phosphatidylserine boosted the response rate for hepatocellular carcinoma (HCC) patients receiving immunotherapy without ....

United States , Paula Calvert , Eugenep Frenkel , Yujin Hoshida , Jay Lohrey , Leticia Khosama , Jakel Hamon , Chul Ahn , Radhika Kainthla , Peter Odonnell Jr , Amitg Singal , Adamc Yopp , Ellen Siglinsky , Heather Kline , David Hsieh , Willisc Maddrey , Mary Claire Maxwell , Courtney Katz , Rolf Brekken , Zhao Zhu , Syedm Kazmi , Hamon Center , Parkland Health , Odonnell School Of Public Health , Clinical Research Manager , Children Medical Center Research Institute ,

Lung cancer treatment shows promise in tumor models

A molecule has demonstrated its ability to kill tumor cells and incite an immune response in preclinical models of small cell lung cancer (SCLC), according to U ....

United States , Mingrui Zhu , Esraa Akbay , Jerryw Shay , Buse Eglenen Polat , Johnd Minna , Lin Xu , Prithvi Raj , Silvia Siteni , Peter Odonnell Jr , Matthew Bender , Victor Stastny , Maxl Thomas , Ryanr Kowash , Benjaminj Drapkin , Charlese Seay , Kenian Chen , Hai Cheng Huang , Shay Lab , Mary Kay Ash Foundation , Research Institute Of Texas , Welch Foundation , Cancer Center Support Grant , Division Of Hematology , Specialized Programs Of Research Excellence , Cancer Research ,

Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors

Induced degradation of lineage-specific oncoproteins drives the therapeutic vulnerability of small cell lung cancer to PARP inhibitors
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