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Why is it so difficult to create anti-aging drugs?

Lengthening telomeres has been raised as a strategy to extend youth, but a new study also links them to an increased risk of cancer ....

United States , University Of California At Berkeley , Johns Hopkins University , Comunidad Autonoma De Cataluna , Washington University , New York , Luis Batista , Nilesh Samani , Dirk Hockemeyer , Mary Armanios , Anderson Cancer Research Center At Rockefeller University , Johns Hopkins University Telomere Center , Regenerative Medicine At Washington University In St , University Of Leicester , Spanish National Cancer Research Center , Autonomous University Of Barcelona , Telomere Therapeutics , Autonomous University , New England Journal , Nature Genetics , Chronic Lymphocytic Leukemia , Titia De Lange , Anderson Cancer Research Center , Rockefeller University , Regenerative Medicine , United Kingdom Biobank ,

Study finds association between severity of COVID-19 and shorter telomeres

Study finds association between severity of COVID-19 and shorter telomeres
Patients with severe COVID-19 disease have significantly shorter telomeres, according to a study conducted by researchers at the Spanish National Cancer Research Centre (CNIO) in collaboration with the COVID-IFEMA Field Hospital, published in the journal
Aging.
The study, led by Maria A. Blasco and whose first authors are Raúl Sánchez and Ana Guío-Carrión, postulates that telomere shortening as a consequence of the viral infection impedes tissue regeneration and that this is why a significant number of patients suffer prolonged sequelae.
Blasco was already developing a therapy to regenerate lung tissue in pulmonary fibrosis patients; she now believes that this treatment -which should still take at least a year and a half to become available- could also help those who have lung lesions remaining after overcoming COVID-19. ....

Comunidad Autonoma De Cataluna , Mariaa Blasco , Emily Henderson , Spanish National Cancer Research Centre , Autonomous University Of Barcelona , Telomerase Group , Autonomous University , Telomere Therapeutics , Gene Therapy , Pulmonary Fibrosis , Sars Cov 2 , காமுனிடட தன்னாட்சி டி கடலுள் , எமிலி ஹென்டர்சன் , ஸ்பானிஷ் தேசிய புற்றுநோய் ஆராய்ச்சி மையம் , தன்னாட்சி பல்கலைக்கழகம் ஆஃப் பார்சிலோனா , தன்னாட்சி பல்கலைக்கழகம் , கீந் சிகிச்சை , நுரையீரல் ஃபைப்ரோஸிஸ் ,

A CNIO study links severe COVID-19 disease to short telomeres

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IMAGE: Human cells with long telomeres (left) and short telomeres (right). Top and lower panels show cells in interphase and in metaphase, respectively.
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Credit: CNIO
Patients with severe COVID-19 disease have significantly shorter telomeres, according to a study conducted by researchers at the Spanish National Cancer Research Centre (CNIO) in collaboration with the COVID-IFEMA Field Hospital, published in the journal
Aging. The study, led by Maria A. Blasco and whose first authors are Raúl Sánchez and Ana Guío-Carrión, postulates that telomere shortening as a consequence of the viral infection impedes tissue regeneration and that this is why a significant number of patients suffer prolonged sequelae. ....

Comunidad Autonoma De Cataluna , Raul Sanchez Vazquez , Santander Universidades , Mariaa Blasco , Paula Mart , Antonio Zapatero Gaviria , Spanish Ministry Of Science , Telomerase Group , Community Of Madrid , Spanish National Cancer Research Centre , Autonomous University Of Barcelona , World Cancer Research , National Institute Of Health Carlos , Banco Santander , Autonomous University , Telomere Therapeutics , Spanish Ministry , National Institute , Health Carlos , World Cancer , Cell Biology , Molecular Biology , Medicine Health , Pulmonary Respiratory Medicine , Gene Therapy , காமுனிடட தன்னாட்சி டி கடலுள் ,