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Scientists Map Genetic Evolution of Chronic Lymphocytic Leukemia to Richter's Syndrome

Scientists Map Genetic Evolution of Chronic Lymphocytic Leukemia to Richter's Syndrome
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Dana-Farber research leads to better understanding of immune system in kidney cancer


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Dana-Farber research leads to better understanding of immune system in kidney cancer
Two research papers highlight single-cell dissection of kidney tumors to identify new immunotherapy treatments and targets
In the last two decades, immunotherapy has emerged as a leading treatment for advanced renal carcinoma cancer (more commonly known as kidney cancer). This therapy is now part of the standard of care, but it doesn’t work for all patients, and almost all patients, no matter how they respond initially, become more resistant to treatment over time. The immune system plays a critical role in kidney cancer disease progression and in response to therapies, and so a fundamental challenge in the field is to understand the underlying “immune circuitry” of this disease. ....

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Dana-Farber research leads to better understanding of the immune system in kidney cancer

Dana-Farber research leads to better understanding of the immune system in kidney cancer
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United States , Dana Farber Cancer Institute , City Of , United Kingdom , Lauren Hirsch , Sara Napolitano , Nicholas Schindler , Davida Braun , Michael Brigham , Dana Farber Brigham , Gabrielle Bouchard , Orit Rozenblatt Rosen , Laura Dellostritto , Angie Mayorga , Van Allen , John Steinharter , Catherinej Wu , Ziad Bakouny , Kellyp Burke , Wenxin Xu , Satyenh Gohil , Lucas Pomerance , Rizwan Haq , Bristol Myers Squibb , Jingyi Wu , Tonik Choueiri ,