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Scientists find promising avenue to restore cognitive function impaired by Alzheimer's disease


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A team of neuroscientists has identified a potential means to address the loss of cognitive function due to Alzheimer s disease by targeting protein synthesis in mice. Their findings, reported in the journal
Science Signaling, reveal that synthetic pharmaceuticals could rescue the activity of brain cells needed for memory formation.
This work is the first to show that reversing impaired protein synthesis in brains afflicted by Alzheimer s disease through a pharmacological approach is not only feasible, but also effective, explains Mauricio Martins-Oliveira, a postdoctoral researcher at New York University s Center for Neural Science and the paper s lead author.
Currently, treatments for Alzheimer s disease center on the reduction of phenomena linked to the affliction, such as amyloid plaque load, neurofibrillary tangles, and neuroinflammation; the ....

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