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Chasing down a cellular 'short circuit'

A group of researchers has identified the cause of a short-circuit in cellular pathways, a discovery that sheds new light on the genesis of a number of human diseases and could lead to development of a wide array of new drugs.

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Department-of-chemistry
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National-institutes-of-health
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Chasing down a cellular 'short circuit'

Chasing down a cellular 'short circuit'
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American
Majid-ghassemian
Suchismita-roy
Ananta-james-silas
Saptarshi-sinha
Pradipta-ghosh
Irina-kufareva
Skaggs-school-of-pharmacy
Drug-administration
National-institutes-of-health
University-of-california-san-diego

Neglected Lipid Tied to Ancient Cell Pathway, Cancer

Neglected Lipid Tied to Ancient Cell Pathway, Cancer
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Cancer-metabolism
Microenvironment-program
Sanford-burnham-prebys
Science-signaling
Raymond-blind

Study shows overlooked lipid is connected to ancient cellular pathway with links to cancer

Within the family of cell membrane lipids known as phosphoinositides and the kinase enzymes that regulate them, phosphoinositide 3-kinases (PI3Ks) have been cast in a starring role as scientists study their involvement in cancer, diabetes and many cellular activities.

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