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Researchers led by a team at NYU Grossman School of Medicine have applied Botox to individual neurons, to help demonstrate how neurons control their own release of dopamine (DA), a chemical messenger involved in motivation, memory, and movement. Through their studies, the team showed that feedback from individual nerve cells controls the release of dopamine. The findings indicate that dopamine-releasing brain cells respond to their own signals to regulate their output of the hormone. This self-regulation through autoinhibition, the researchers suggest, stands in contrast to the widely held view that mechanisms for controlling the release of dopamine the “feel good” hormone by any individual cell rely on feedback from nearby cells effectively recognizing how much is being released. ....
Brain Cells Decide on Their Own When to Release Pleasure Hormone News provided by Share this article Share this article NEW YORK, April 6, 2021 /PRNewswire/ In addition to smoothing out wrinkles, researchers have found that the drug Botox can reveal the inner workings of the brain. A new study used it to show that feedback from individual nerve cells controls the release of dopamine, a chemical messenger involved in motivation, memory, and movement. Such self-regulation, the researchers say, stands in contrast to the widely held view that the release of dopamine known as the feel good hormone by any cell relied on messages from nearby cells to recognize that it is releasing too much of the hormone. ....