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MET status may predict benefit of amivantamab-lazertinib therapy in lung cancer subset

CHICAGO — MET status by immunohistochemistry may predict how patients with osimertinib-treated EGFR-mutated non-small lung cancer will respond to subsequent combination therapy, according to findings presented at ASCO Annual Meeting.Patients with MET-positive status appeared five times as likely as those with MET-negative status to respond to amivantamab (Rybrevant, Janssen) plus lazertinib ....

United States , Vamsidhar Velcheti , Chugai Pharma , Bymark Leiser , Benjamin Besse , Daiichi Sankyo , Mindy Valcarcel , Roche Genentech , Institute Gustave Roussy , Aptitude Health , Janssen Oncology , Taiho Pharmaceutical ,