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New drug combination may prevent GvHD after stem cell transplantation for blood cancers

A drug combination can safely prevent transplanted stem cells, known as a graft, from attacking the recipient's body, allowing them to develop into healthy new blood and immune cells, a new study shows. ....

United States , Judithd Goldberg , Mohammad Maher Abdul , Bristol Myers Squibb , Emily Henderson , Samer Al Homsi , Ja Suarez Londono , Benedetto Bruno , Kelli Cole , Daichii Sankyo , Kelsey Stocker , Frank Cirrone , Langone Health , Isaac Perlmutter Cancer Center , Jazz Pharmaceuticals , Marrow Transplant Program , American Society Of Hematology , Grossman School Of Medicine , Lisa Dean Moseley Foundation , Department Of Medicine , Perlmutter Cancer Center , Perlmutter Cancer , American Society , Mohammad Maher Abdul Hay , Lisa Dean Moseley , Abdul Hay ,

Genetic study predicts optimal use of 'Tacrolimus' for kidney transplant patients

The dose prediction study was focused on the immunosuppressant drug tacrolimus, which is given to a kidney, heart or liver transplant patient to lower the body s immunity and thereby considerably reducing the chances of organ rejection. ....

Chandrabhas Narayana , Radhakrishnan Nair , Alekshmy Srinivas , Alekshmy Srinivas , Rajiv Gandhi Centre For Biotechnology , Noble Gracious Of The Department Nephrology , Engineering Research Board , Division Of Laboratory Medicine , Government Medical College , Kidney Transplant , Rajiv Gandhi Centre , Laboratory Medicine , Molecular Diagnostics , Noble Gracious , Immunosuppressant Drug , Rug For Kidney Transplant Patients , Enetic Study On Kidney Disease , Rgan Rejection Risk , Liver Transplant , Heart Transplant ,

Study demonstrates that the main creators of SARS-CoV-2 mutations are vaccine-suppressed

Study demonstrates that the main creators of SARS-CoV-2 mutations are vaccine-suppressed
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to wreak its havoc the world over, seemingly remaining one step ahead of scientists. With the rollout of SARS-CoV-2 vaccines, the focus shifted to making vaccines available in the vast quantities required for the global immunization effort.
However, the emergence of multiple antibody-resistant mutants has cast doubts on the success of this strategy. Especially concerning are the three variants of concern (VOCs), namely, B.1.1.7 (20I/501Y.V1), B.1.351 (20H/501Y.V2), and P1 (20J/501Y.V3).
A new research paper posted to the ....

South Africa , Liji Thomas , Image Credit , Northern Jersey , New England Journal , Ars Cov 2 , Ngiotensin Converting Enzyme 2 , Binding Affinity , Convalescent Plasma , Coronavirus Disease Covid 19 , Immune Response , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Spike Protein , படம் கடன் , வடக்கு ஜெர்சி , புதியது இங்கிலாந்து இதழ் ,

Long-term steroid treatment may not be necessary for kidney transplant patients

Long-term steroid treatment may not be necessary for kidney transplant patients
Long-term use of a medication used to treat kidney transplant patients may not be necessary in individuals with low-to-moderate risk of organ rejection, according to the results of a study led by a University of Cincinnati transplant researcher.
The randomized clinical trial of 385 patients on immunosuppressive drugs tacrolimus and mycophenolate examined whether use of these medicines called corticosteroids could be eliminated at seven days after kidney transplantation.
The study shows that 15 years after transplantation no difference in kidney transplant survival or patient survival rates were found between patients who received long-term corticosteroids versus those who had corticosteroid eliminated early, explains E. Steve Woodle, MD, the William A. Altemeier Endowed Chair and Professor of Surgery in the UC College of Medicine, and leader of the study. ....

United States , Rita Alloway , Williama Altemeier , E Steve Woodle , Emily Henderson , University Of Cincinnati , Uc Division Of Nephrology , Uc Health , Uc College Of Medicine , Endowed Chair , Clinical Trial , Kidney Transplant , ஒன்றுபட்டது மாநிலங்களில் , ரீட்டா அல்லோவாய் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் ஸிந்ஸந்யாடீ , அக் பிரிவு ஆஃப் நெப்ராலஜி , அக் ஆரோக்கியம் , அக் கல்லூரி ஆஃப் மருந்து , வழங்கப்பட்டது நாற்காலி , மருத்துவ சோதனை , நீரிழிவு நோய் , கிட்நீ மாற்று , அறுவை சிகிச்சை ,

Researchers design armored immune cells to attack recurring cancer in liver transplant patients

Researchers design armored immune cells to attack recurring cancer in liver transplant patients
Duke-NUS Medical School researchers, together with collaborators in Singapore, have designed armored immune cells that can attack recurring cancer in liver transplant patients, while temporarily evading immunosuppressant drugs patients take to avoid organ rejection. The findings were published in the journal
Hepatology.
Hepatocellular carcinoma is the most common type of primary liver cancer and the sixth most common cancer worldwide. It often develops in people with chronic liver disease following hepatitis B infection.
A common treatment for hepatocellular carcinoma is to completely remove the liver and replace it with a healthy one from a donor. However, hepatitis B-related hepatocellular carcinoma can recur in some patients following transplantation. To kill the cancer, doctors can inject immune cells, called T cells, which are specially designed to target hepatitis ....

Patrick Casey , Antonio Bertoletti , Emily Henderson , Dean For Research , Infectious Diseases Programme , Professor Antonio Bertoletti , Emerging Infectious Diseases , Prof Bertoletti , Senior Vice Dean , Hepatitis B , Hepatocellular Carcinoma , Liver Cancer , Liver Disease , Liver Transplant , Medical School , பேட்ரிக் வழக்கு , எமிலி ஹென்டர்சன் , டீன் க்கு ஆராய்ச்சி , தொற்று நோய்கள் ப்ரோக்ராம் , வளர்ந்து வருகிறது தொற்று நோய்கள் , மூத்தவர் துணை டீன் , கல்லீரல் புற்றுநோய் , கல்லீரல் நோய் , கல்லீரல் மாற்று , மருத்துவ பள்ளி ,