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Transplant patients may not need steroid treatment in the long run


Credit: Colleen Kelley/University of Cincinnati
Long-term use of a medication used to treat kidney transplant patients may not be necessary in individuals with low-to-moderate risk of organ rejection, according to the results of a study led by a University of Cincinnati transplant researcher.
The randomized clinical trial of 385 patients on immunosuppressive drugs tacrolimus and mycophenolate examined whether use of these medicines called corticosteroids could be eliminated at seven days after kidney transplantation. The study shows that 15 years after transplantation no difference in kidney transplant survival or patient survival rates were found between patients who received long-term corticosteroids versus those who had corticosteroid eliminated early, explains E. Steve Woodle, MD, the William A. Altemeier Endowed Chair and Professor of Surgery in the UC College of Medicine, and leader of the study. ....

United States , Rita Alloway , Astellas Pharma , Darren Stewart , John Gill , Williama Altemeier , E Steve Woodle , Stephanie Clark , University Of Cincinnati , Uc Division Of Nephrology , Uc Health , Uc College Of Medicine , Canadian Institutes Of Health Research , Endowed Chair , Roy First , Canadian Institutes , Medicine Health , Internal Medicine , Public Health , ஒன்றுபட்டது மாநிலங்களில் , ரீட்டா அல்லோவாய் , டேரன் ஸ்டீவர்ட் , ஜான் கில் , மாற்றாந்தாய் கிளார்க் , பல்கலைக்கழகம் ஆஃப் ஸிந்ஸந்யாடீ , அக் பிரிவு ஆஃப் நெப்ராலஜி ,

Long-term steroid treatment may not be necessary for kidney transplant patients


Long-term steroid treatment may not be necessary for kidney transplant patients
Long-term use of a medication used to treat kidney transplant patients may not be necessary in individuals with low-to-moderate risk of organ rejection, according to the results of a study led by a University of Cincinnati transplant researcher.
The randomized clinical trial of 385 patients on immunosuppressive drugs tacrolimus and mycophenolate examined whether use of these medicines called corticosteroids could be eliminated at seven days after kidney transplantation.
The study shows that 15 years after transplantation no difference in kidney transplant survival or patient survival rates were found between patients who received long-term corticosteroids versus those who had corticosteroid eliminated early, explains E. Steve Woodle, MD, the William A. Altemeier Endowed Chair and Professor of Surgery in the UC College of Medicine, and leader of the study. ....

United States , Rita Alloway , Williama Altemeier , E Steve Woodle , Emily Henderson , University Of Cincinnati , Uc Division Of Nephrology , Uc Health , Uc College Of Medicine , Endowed Chair , Clinical Trial , Kidney Transplant , ஒன்றுபட்டது மாநிலங்களில் , ரீட்டா அல்லோவாய் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் ஸிந்ஸந்யாடீ , அக் பிரிவு ஆஃப் நெப்ராலஜி , அக் ஆரோக்கியம் , அக் கல்லூரி ஆஃப் மருந்து , வழங்கப்பட்டது நாற்காலி , மருத்துவ சோதனை , நீரிழிவு நோய் , கிட்நீ மாற்று , அறுவை சிகிச்சை ,