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Mini-Colons Transform Colorectal Cancer Studies

Mini-Colons Transform Colorectal Cancer Studies
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Nicolas Broguiere , Jakob Langer , Freddy Radtke , Lucie Tillard , Matthiasp Lutolf , Mikhail Nikolaev , L Francisco Lorenzo Mart , Luis Francisco Lorenzo Mart , Roche Institute Of Human Biology , Swiss Cancer Center Leman , Roche Innovation Center Basel , Institute Of Human Biology , Swiss Institute For Experimental Cancer Research , Experimental Cancer Research , Cancer Center Leman , Human Biology , Roche Innovation Center , Francisco Lorenzo Mart ,

Protein behind immunotherapy resistance

Protein behind immunotherapy resistance
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Agnieszka Chryplewicz , Douglas Hanahan , Opna Bio , National Center , Swiss Institute For Experimental Cancer Research , Agora Cancer Research Center , Swiss Institute Of Bioinformatics , Swiss Cancer Center Leman , Ludwig Institute Of Cancer Research , University Of Bern , University Of Lausanne , Jeremy Guillot Hanahan Lab , University Hospital Of Lausanne , Children Health , Jeremy Guillot , Hanahan Lab , Ludwig Institute , Cancer Research , Swiss Institute , Experimental Cancer Research , Lausanne Branch , University Hospital , Cancer Center Leman ,

Cancer cells hijack 3D structure of DNA

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Cancer cells hijack 3D structure of DNA
Scientists at EPFL and UNIL have used a novel algorithmic approach on cancer cells to understand how changes in histone marks (H3K27ac) induce repositioning of chromatin regions in the cell nucleus, and described how modifications of local contacts between regulatory elements (enhancers and promoters) influence oncogene expression.
In cancer, a lot of biology goes awry: Genes mutate, molecular processes change dramatically, and cells proliferate uncontrollably to form entirely new tissues that we call tumors. Multiple things go wrong at different levels, and this complexity is partly what makes cancer so difficult to research and treat. ....

United States , Giovanni Ciriello , Elisa Oricchio , Alexander Calder , Nature Communications , Swiss Cancer Center Leman , Swiss Institute Of Bioinformatics , Aix Marseille University , University Of Lausanne , Nature Genetics , Marseille University , ஒன்றுபட்டது மாநிலங்களில் , ஜியோவானி சிரியெல்லோ , அலெக்சாண்டர் கால்டர் , இயற்கை தகவல்தொடர்புகள் , சுவிஸ் புற்றுநோய் மையம் லெமன் , சுவிஸ் நிறுவனம் ஆஃப் உயிர் தகவலியல் , ஐஸ் மார்சேய் பல்கலைக்கழகம் , இயற்கை ஜெநெடிக்ஸ் , மார்சேய் பல்கலைக்கழகம் ,

Cancer cells hijack the 3D structure of DNA

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In cancer, a lot of biology goes awry: Genes mutate, molecular processes change dramatically, and cells proliferate uncontrollably to form entirely new tissues that we call tumors. Multiple things go wrong at different levels, and this complexity is partly what makes cancer so difficult to research and treat.
So it stands to reason that cancer researchers focus their attention where all cancers begin: the genome. If we can understand what happens at the level of DNA, then we can perhaps one day not just treat but even prevent cancers altogether.
This drive has led a team of researchers from EPFL and the University of Lausanne (UNIL) to make a breakthrough discovery concerning a critical genetic aberration that occurs in cancer. Working together, the groups of Elisa Oricchio (EPFL) and Giovanni Ciriello (UNIL) have used a novel algorithm-based method to study how cancer cells re-organize the 3D structure of their DNA in order to ramp up the activity of cancer- ....

United States , Giovanni Ciriello , Elisa Oricchio , Alexander Calder , Nature Communications , Swiss Cancer Center Leman , Swiss Institute Of Bioinformatics , Aix Marseille University , University Of Lausanne , Nature Genetics , Cancer Center Leman , Marseille University , ஒன்றுபட்டது மாநிலங்களில் , ஜியோவானி சிரியெல்லோ , அலெக்சாண்டர் கால்டர் , இயற்கை தகவல்தொடர்புகள் , சுவிஸ் புற்றுநோய் மையம் லெமன் , சுவிஸ் நிறுவனம் ஆஃப் உயிர் தகவலியல் , ஐஸ் மார்சேய் பல்கலைக்கழகம் , இயற்கை ஜெநெடிக்ஸ் , மார்சேய் பல்கலைக்கழகம் ,