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Epigenome Editing Decreases Alcohol Seeking and Anxiety in Rats

A CRISPR-based system that reverses epigenetic changes caused by adolescent binge drinking reduces adult addiction-like behaviors in rats, a study finds, suggesting that an epigenomic approach could someday help treat people with alcohol use disorder. ....

Comunidad Autonoma De Cataluna , Elizabeth Heller , Elena Martin Garcia , Subhash Pandey , University Of Illinois , University Of Pennsylvania , University Of Illinois At Chicago , University Of Pompeau Fabra , Pompeau Fabra ,

CRISPR can reverse epigenetic changes caused by adolescent binge drinking

CRISPR can reverse epigenetic changes caused by adolescent binge drinking
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United States , Jessica Peixinho , Subhash Pandey , Centre For Alcohol Research In Epigenetics , University Of Illinois Chicago , Illinois Chicago , Professor Subhash Pandey , Alcohol Research , Science Advances ,

"Factory reset" for the brain rewrites risk of anxiety and alcohol abuse

An intriguing new study has zeroed in on a brain region that is central to the development of both alcohol abuse and anxiety in adults, and demonstrated how gene editing could be used to wipe clean a person's predisposition to both disorders. ....

United States , Subhash Pandey , University Of Illinois Chicago , Illinois Chicago ,

CRISPR tool reverse one big consequence of "teenage" drinking in mouse brains

Researchers have used a CRISPR-Cas9 tool to repair epigenetic damage from "teenage" drinking in mice. ....

Collin Teague , Eric Nestler , Subhash Pandey , Crispr Cas9 , Teenage Drinking , Epigenetic Remodeling ,

A 'factory reset' for the brain cures anxiety, drinking behavior

Gene editing may be a potential treatment for anxiety and alcohol use disorder in adults who were exposed to binge drinking in their adolescence, according to t ....

United States , Amy Lasek , Huaibo Zhang , John Peyton Bohnsack , Josepha Flaherty , Evan Kyzar , Gabriela Wandling , Subhash Pandey , Alcohol Research In Epigenetics , National Institute On Alcohol Abuse , University Of Illinois Chicago , Department Of Veterans Affairs , Jesse Brown Va Medical Center , Illinois Chicago , Endowed Professor , Alcohol Research , Jesse Brown , National Institute , Alcohol Abuse , Inge Drinking Anxiety Alcohol Use Disorder Alcoholism Gene Editing Crispr Dcas9 , Alcohol And Alcoholism , All Journal News , Behavioral Science , Sychology And Psychiatry , Ational Institute On Alcohol Abuse And Alcohoasm Niaaa , University Of Illinois Chicago ,