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Targeted therapy for children with high-risk Hodgkin lymphoma reduces relapse rates, trial shows

A targeted therapy for children with high-risk Hodgkin lymphoma (HL) was shown to significantly reduce relapse rates when tested in a large multicenter clinical trial conducted by the Children's Oncology Group (COG) and led by pediatric oncologists at Roswell Park Comprehensive Cancer Center, Children's Healthcare of Atlanta and Winship Cancer Institute of Emory University. By combining the targeted antibody-drug conjugate (ADC) brentuximab vedotin (BV) with the standard chemotherapy regimen, children were 10% less likely to relapse. ....

Sharon Castellino , Kara Kelly , Allison Brashear , Frank Keller , Emily Henderson , National Cancer Institute , Emory University , Lymphoma Program , Emory University School Of Medicine , Blood Disorders Program , Winship Cancer Institute Of Emory University , Hodgkin Committee Chair , Health Sciences , Division Of Cancer Treatment , Jacobs School Of Medicine , Development Agreement , Roswell Park Comprehensive Cancer Center , Blood Disorders Center , National Institutes Of Health , Children Oncology Group , Biomedical Sciences , Dean Of The Jacobs School Medicine , Baldrick Foundation , Department Of Pediatrics , University At Buffalo , Oncology Group ,

Discovery could play an important role in future medicines to heal damaged hearts

Scientists at the UNC School of Medicine have made a significant advance in the promising field of cellular reprogramming and organ regeneration, and the discovery could play a major role in future medicines to heal damaged hearts. ....

Chaofei Wang , Li Qian , Emily Henderson , School Of Medicine , University Of North Carolina At Chapel Hill , Lab Medicine , Department Of Pathology , Mcallister Heart Institute , Cell Stem , North Carolina , Chapel Hill , Study Senior , Benjamin Keepers , Heart Attack , Heart Disease , Heart Failure , Stem Cells ,

Microtubule regulatory protein inhibits early HIV-1 infection, study finds

Northwestern Medicine investigators have discovered that a microtubule regulatory protein inhibits early HIV type 1 (HIV-1) infection, according to findings published in Proceedings of the National Academy of Sciences. ....

Mojgan Naghavi , Emily Henderson , Proceedings Of The National Academy Sciences , Roberth Lurie Comprehensive Cancer Center , Northwestern University , National Academy , Comprehensive Cancer Center , Study Senior , Hiv 1 ,