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Targeted therapy for children with high-risk Hodgkin lymphoma reduces relapse rates, trial shows

A targeted therapy for children with high-risk Hodgkin lymphoma (HL) was shown to significantly reduce relapse rates when tested in a large multicenter clinical trial conducted by the Children's Oncology Group (COG) and led by pediatric oncologists at Roswell Park Comprehensive Cancer Center, Children's Healthcare of Atlanta and Winship Cancer Institute of Emory University. By combining the targeted antibody-drug conjugate (ADC) brentuximab vedotin (BV) with the standard chemotherapy regimen, children were 10% less likely to relapse. ....

Sharon Castellino , Kara Kelly , Allison Brashear , Frank Keller , Emily Henderson , National Cancer Institute , Emory University , Lymphoma Program , Emory University School Of Medicine , Blood Disorders Program , Winship Cancer Institute Of Emory University , Hodgkin Committee Chair , Health Sciences , Division Of Cancer Treatment , Jacobs School Of Medicine , Development Agreement , Roswell Park Comprehensive Cancer Center , Blood Disorders Center , National Institutes Of Health , Children Oncology Group , Biomedical Sciences , Dean Of The Jacobs School Medicine , Baldrick Foundation , Department Of Pediatrics , University At Buffalo , Oncology Group ,

Pediatric Multicenter Study Shows Targeted Therapy for High-Risk Hodgkin Lymphoma Reduces Relapse

Buffalo, NY, and Atlanta, GA (PRWEB) November 02, 2022 BUFFALO, N.Y., and ATLANTA, Ga. A targeted therapy for children with high-risk Hodgkin lymphoma ....

New York , United States , New Zealand , Emory University , Emory University School Of Medicine , Roswell Park , Sharon Castellino , Kara Kelly , Allison Brashear , Frank Keller , Physician Group , National Cancer Institute , Lymphoma Program , Winship Cancer Institute Of Emory University , Hodgkin Committee Chair , University Of New York , Health Sciences , Roswell Park Comprehensive Cancer Center , National Clinical Trials Network , National Institutes Of Health , Statistics Data Center Grant , Department Of Pediatrics , University At Buffalo , Operations Center Grant , Blood Disorders Program , National Cancer Comprehensive Center ,