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B cell response after influenza vaccine in young and older adults

B cell response after influenza vaccine in young and older adults
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United States , Hailong Meng , Meng Wang , Subhasis Mohanty , Ruoyi Jiang , Stevenh Kleinstein , Albertc Shaw , Yale University School Of Medicine , Yale University , Yale School ,

Why Does COVID-19 Cause Severe Illness in Some Patients but Not Others?

A new study harnesses big data and bioinformatics to explore how the immune system can fight off the virus in some cases and fails in others. ....

Anderson Brito , Anna Konstorum , Chris Cotsapas , Ruthr Montgomery , Stevenh Kleinstein , Anthonyn Brady , Leying Guan , Nathan Grubaugh , Bernie Chen , Albertc Shaw , Denise Esserman , Shrikant Pawar , Jeremyp Gygi , Davida Hafler , Lois Stiles Edgerly , National Institute Of Allergy , Human Immunology Project Consortium , Phenotyping Assessment , National Institute , Infectious Diseases , Lois Stiles Edgerly Professor , Cell Reports Medicine , Phenotying Assessment , Post Acute Sequelae ,

New methods can advance the development of rapid diagnostics for many infectious diseases

Two companion studies report new artificial intelligence approaches for identification of molecular "fingerprints" for specific infections. The methods, used here to derive a fingerprint for COVID-19, can advance the development of rapid diagnostics for many infectious diseases. ....

Stevenh Kleinstein , Elena Zaslavsky , Emily Henderson , Yale School Of Medicine , Program In Computational Biology , Icahn School Of Medicine At Mount Sinai , Bioinformatics Yale University , Associate Professor , Icahn School , Mount Sinai , Anthony Brady Professor , Yale School , Computational Biology , Bioinformatics Yale , Discovery Industry Focus , Artificial Intelligence , Covid 19 , Infectious Diseases , Ars Cov 2 ,

Steven H. Kleinstein appointed Anthony N. Brady Professor of Pathology

Kleinstein has made fundamental contributions to immunology through the development and application of innovative computational methods. ....

Stevenh Kleinstein , Anthonyn Brady , Yale School Of Medicine Department Pathology , Data Analysis Working Group , National Institute Of Allergy , National Institutes Of Health , Princeton University , Advisory Committee , Us Israel Binational Science Foundation , Efficacy Program , Program In Computational Biology , Human Immunology Project Consortium , Receptor Plus Consortium , Defense Advanced Research Projects Agency , Department Of Immunobiology , Yale School , Computational Biology , Science Translational Medicine , National Institutes , Israel Binational Science Foundation , Executive Committee , Adaptive Immune Receptor Repertoire , Scientific Advisory Board , Bioinformatics Integration Support Contract , External Advisory Committee , National Institute ,

Researchers Connect Spinal Fluid Autoantibodies to Neurological Symptoms in COVID-19 Patients

February 15, 2021
by Julie Parry
In March of 2020, Shelli Farhadian, MD, PhD, assistant professor of medicine (infectious diseases) and neurology, began to see parallels in her pre-pandemic research on neurologic effects in patients with HIV infection and the possibility of neurologic effects on patients with SARS-CoV-2, or COVID-19.
“There was some literature out there that suggested that coronaviruses could have an effect on the brain. So, knowing that that was a potential possibility, even before we had our first case at Yale New Haven Hospital, I worked with other people to set up a protocol where we could consent patients to collect tissue specimens and information to try to see if this was also going happen with SARS-CoV-2,” explained Farhadian. ....

New York , United States , San Francisco , Bretts Phinney , Jennifer Chiarella , Ravi Dandekar , Benjamin Goldman Israelow , Isobela Hawes , Yile Dai , Jon Klein , Alberti Ko , Christopher Bartley , Michelle Salemi , Todd Lencz , Lindsay Mcalpine , Colinr Zamecnik , Nur Taz Rahman , Chantalbf Vogels , Hannah Walsh , Christopherm Bartley , Tianyang Mao , Serena Spudich , Josephl Derisi , Stevenh Kleinstein , Juana Gallego , Ryand Chow ,