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Newly discovered bacterial communication system aids antimicrobial resistance

Researchers discovered a stress signaling system that enables bacteria to adapt and protect themselves against the immune system and certain antibiotics. The discovery of RlmN as a stress sensor reveals a new mechanism of antimicrobial resistance that can be targeted for drug development. ....

Peter Dedon , Lee Wei Lin , Alliance For Research , Nanyang Technological University Singapore , Singapore Center , Nature Communications , National Research Foundation , Environmental Life Sciences Engineering , Campus For Research Excellence And Technological Enterprise , Antimicrobial Resistance , Nanyang Technological University , Research Excellence And Technological Enterprise , Mit Smart , Smart Amr , Ingapore Mit Alliance For Research And Technology , Antimicrobial Resistance Amr , Edon Laboratory , Peter Dedon , Eactive Oxygen Species Ros , Drug Resistance , Drug Development , Antibiotic Resistant Bacteria , Nterococcus Faecalise Faecalis , Tress Signalling , Lee Wei Lin ,

A novel combination therapy for treating vancomycin-resistant bacterial infections

Researchers developed a combination therapy using the anticancer agent mitoxantrone (MTX), together with an antibiotic, vancomycin, for treating vancomycin-resistant Enterococcus faecalis or VRE. ....

Jianzhu Chen , Innovation Centre , Energy Electronic Systems , Alliance For Research , Nanyang Technological University , Singapore Centre For Environmental Life Sciences Engineering , National Research Foundation Of Singapore , Campus For Research Excellence , University Of Geneva , Koch Institute For Integrative Cancer Research , Antimicrobial Resistance , Singapore Centre , Environmental Life Sciences Engineering , Koch Institute , Integrative Cancer , National Research Foundation , Research Excellence , Technological Enterprise , Critical Analytics , Manufacturing Personalized Medicine , Sustainable Technologies , Agricultural Precision , Future Urban Mobility , Low Energy Electronic , Smart Amr , Ingapore Mit Alliance For Research And Technology ,

A novel combination therapy for treating vancomycin-resistant bacterial infections

Researchers developed a combination therapy using the anticancer agent mitoxantrone (MTX), together with an antibiotic, vancomycin, for treating vancomycin-resistant Enterococcus faecalis or VRE. ....

Jianzhu Chen , National Research Foundation Of Singapore , Nanyang Technological University , Innovation Centre , Alliance For Research , Campus For Research Excellence , Koch Institute For Integrative Cancer Research , Singapore Centre For Environmental Life Sciences Engineering , University Of Geneva , Energy Electronic Systems , Antimicrobial Resistance , Singapore Centre , Environmental Life Sciences Engineering , Koch Institute , Integrative Cancer , National Research Foundation , Research Excellence , Technological Enterprise , Critical Analytics , Manufacturing Personalized Medicine , Sustainable Technologies , Agricultural Precision , Future Urban Mobility , Low Energy Electronic , Smart Amr , Ingapore Mit Alliance For Research And Technology ,