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The Rebel Russian Behind the Microbiome and Probiotics

Nautilus is a different kind of science magazine. We deliver big-picture science by reporting on a single monthly topic from multiple perspectives. Read a new chapter in the story every Thursday.

Myeloid Therapeutics Launches with Over $50 Million in Financing and Two Clinical Trials

Myeloid Therapeutics Launches with Over $50 Million in Financing and Two Clinical Trials Myeloid s cell therapy harnesses the innate capabilities of myeloid lineage cells to fight cancer Scientific founders include world-renowned cell therapy & cancer experts Ronald Vale, Ph.D. and Siddhartha Mukherjee, M.D., D.Phil. Co-Founded by Thomas Cahill, M.D., Ph.D., with financing led by Newpath Partners and participation from leading biotech investors News provided by Share this article Share this article CAMBRIDGE, Mass., Jan. 6, 2021 /PRNewswire/ Myeloid Therapeutics, Inc., a company harnessing and reprogramming myeloid cells for treating cancers, launched today with over $50 million in financing to initiate multiple clinical trials in 2021. The Company combines advanced gene and cell engineering capabilities with substantial biologics knowledge to elucidate and redirect the power of myeloid cells to treat cancers, particularly solid tumors and those that are poorly served by exi

Elie Metchnikoff, the Man and the Myth - FullText - Journal of Innate Immunity 2016, Vol 8, No 3

Abstract The year 2016 marks the centenary of the death of Elie Metchnikoff, the father of innate immunity and discoverer of the significance of phagocytosis in development, homeostasis and disease. Through a series of intravital experiments on invertebrates and vertebrates, he described the role of specialised phagocytic cells, macrophages and microphages, subsequently renamed neutrophils and polymorphonuclear leucocytes, in the host response to injury, inflammation, infection and tissue repair. As a vigorous proponent of cellular immunity, he championed its importance versus humoral immunity in the so-called antibody wars. By 1908, when the Nobel Prize was awarded to Elie Metchnikoff and Paul Ehrlich, this debate was not yet resolved. Even earlier, Metchnikoff had turned his research interests to the process of ageing and the possible link to intestinal auto-intoxication, giving rise to the current interest in the microbiome of the gut and the use of probiotics to promote health a

Orchard Therapeutics : New Horizons in Gene Therapy

Orchard Therapeutics : New Horizons in Gene Therapy
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