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SGLT2 Inhibitors Could Play a Role in Treating Gout

A new review considers how SGLT2 inhibitors like dapagliflozin and empagliflozin have been shown to clinically improve gout while reducing its cardiometabolic and renal comorbidities. ....

United States , Chio Yokose , Campbellp Dapagliflozin , Merck Ertugliflozin , Campbellp Empagliflozin Jardiance , Mongan Institute , European Congress On Rheumatology , Drug Administration , Rheumatology Allergy Clinical Epidemiology Research Center , Allergy Clinical Epidemiology Research Center , Massachusetts General Hospital , European Congress , Nat Rev Rheumatol , Published December , Reducing Risk , Published October , Published September , Could Lower Gout , Published June ,

Empagliflozin Shows Promise As An Adjunct To Selective Serotonin Reuptake Inhibitors In Reducing Symptom Severity In Major Depressive Disorder

1. Combination therapy of empagliflozin and citalopram reduced symptom severity in patients with major depressive disorder. 2. This average reduction in symptom severity was statistically significant over time in comparison to the reduction of symptoms seen in the placebo-citalopram group. Evidence Rating Level: 1 (Excellent) Antidepressants like selective serotonin reuptake inhibitors (SSRIs) are presently first-line ....

Minute Medicine Inc , Rating Level , Hamilton Depression Rating Scale ,

Non-Insulin Diabetes Medications Safe for Infants in Early Pregnancy

Multinational data support the safety of drug classes like GLP-1 agonists during early relative to infant risk of major congenital malformations. ....

Researchgate Carolyn , Centre For Pharmacoepidemiology At Karolinska Institute , Karolinska Institute , Type 2 ,

SGLT2 Inhibition May Reduce Albuminuria in Young Patients with Alport Syndrome

Data presented at ASN Kidney Week 2023 described the effects of SGLT2 inhibition in young patients with Alport syndrome. ....

United States , Oliver Gross , American Society Of Nephrology Kidney Week , American Society , Nephrology Kidney Week , Medical Center , Chronic Kidney Disease , Alport Syndrome ,

SGLT2 Inhibitors Reduce Proteinuria in Patients with IgA Nephropathy

Patients with IgA nephropathy experienced nearly 30% proteinuria reduction after 6 months of treatment with SGLT2 inhibitors. ....

Yaping Dong , University First Hospital , National Kidney Foundation , Peking University First Hospital , Peking University First , From April , Accessed October , Sglt2 Inhibitor , Iga Nephropathy , Sodium Glucose Cotransport 2 , Immunoglobulin A ,