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Reviewed This Month Prehospital Blood Product and Crystalloid Resuscitation in the Severely Injured Patient: A Secondary Analysis of the Prehospital Air Medical Plasma Trial Authors: Guyette FX, Sperry JL, Peitzman AB, et al. Published in: Ann Surg, 2021 Feb 1; 273(2): 358–64 Hemorrhage is the leading cause of preventable death following injury. Historically, crystalloid fluids were our primary method of treating patients suffering significant loss of blood. However, the Prehospital Air Medical Plasma (PAMPer) trial found that prehospital administration of plasma during resuscitation reduced 30-day mortality of severely injured patients by almost 10%. Data from other studies have shown packed red blood cells (PRBCs), plasma, and platelets also can improve outcomes for patients at risk for hemorrhagic shock. ....