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La asistencia compartida mejora exponencialmente la asistencia a pacientes quirúrgicos graves con comorbilidades

La asistencia compartida mejora exponencialmente la asistencia a pacientes quirúrgicos graves con comorbilidades
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U S Food and Drug Administration Approves Opdivo® (nivolumab) as Adjuvant Treatment of Completely Resected Esophageal or Gastroesophageal Junction Cancer in Patients who have Received Neoadjuvant Chemoradiotherapy | Antibodies

In CheckMate -577, Opdivo 1 Approval expands the role of Opdivo in earlier stages of disease, with two indications in the adjuvant setting across three types of cancer 1 PRINCETON, NJ, USA I May 20, 2021 I Bristol Myers Squibb (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) has approved Opdivo ® (nivolumab, injection for intravenous use) for the adjuvant treatment of completely resected esophageal or gastroesophageal junction (GEJ) cancer with residual pathologic disease in patients who have received neoadjuvant chemoradiotherapy (CRT). 1 The approval is based on results from the Phase 3 CheckMate -577 trial that evaluated Opdivo (n=532) compared to placebo (n=262) in esophageal or GEJ cancer patients with residual pathologic disease following neoadjuvant CRT and complete resection.

Baylor universityUnited statesSouth koreaRonanj kellyAdam lenkowskyI bristol myers squibbNeoadjuvant downstagingNeoadjuvant chemoradiotherapyGastroenterol hepatolBristol myers squibbWw caruth jrAssociation with baseline variablesBristol myers squibb companyTime oncology review pilot programVirtual congressDrug administration approves opdivo

Journal Watch: Blood Products vs Crystalloid for Resuscitation

Reviewed This Month Prehospital Blood Product and Crystalloid Resuscitation in the Severely Injured Patient: A Secondary Analysis of the Prehospital Air Medical Plasma Trial Authors: Guyette FX, Sperry JL, Peitzman AB, et al. Published in: Ann Surg, 2021 Feb 1; 273(2): 358–64 Hemorrhage is the leading cause of preventable death following injury. Historically, crystalloid fluids were our primary method of treating patients suffering significant loss of blood. However, the Prehospital Air Medical Plasma (PAMPer) trial found that prehospital administration of plasma during resuscitation reduced 30-day mortality of severely injured patients by almost 10%. Data from other studies have shown packed red blood cells (PRBCs), plasma, and platelets also can improve outcomes for patients at risk for hemorrhagic shock.

Reviewed thisBlood productCrystalloid resuscitationSeverely injured patientSecondary analysisPrehospital air medical plasmaAnn surgEmergency medical servicesPacked red blood cellsஇரத்தம் ப்ராடக்ட்இரண்டாம் நிலை பகுப்பாய்வுபிரேஹொஸ்பிட்டள் அேக மருத்துவ பிளாஸ்மாஆண்டு சர்ஜ்