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New ICD-10 Code is An Important Milestone for Rare Disease Patients

The introduction of an ICD-10 code specific to IgG4-Related Disease offers a promising opportunity to revolutionize patient care, enable more accurate diagnoses, and improve outcomes. ....

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Cureus | A Case Report of a Prevertebral Mass in an Elderly Male Post Hodgkin's Lymphoma

Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory autoimmune disease characterized by tissue infiltration by dense lymphoplasmacytic infiltrate composed of T cells, activated B-cells, and plasma cells expressing IgG4 and has varied presentations with similar histopathology. It can involve visceral organs, glands, aorta, lymph nodes, and retroperitoneal tissue. In our case, a 68-year-old male with a past history of Hodgkin's lymphoma and in remission presented for investigation of polyclonal gammopathy. Serum electrophoresis showed increased free kappa light chains, free lambda light chains, and kappa lambda ratio; immunoglobulin G (IgG) levels were also increased. A positron emission tomography (PET) scan and magnetic resonance imaging (MRI) thoracic spine suggested a hypermetabolic prevertebral soft tissue density. Biopsy of the mass suggested IgG4-related disease (IgG4-RD). He also had a compression fracture of the T7 vertebra. He was started on intravenous me ....

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Clinical characteristics of 37 Cases IgG4-Related Disease

Analyzing the clinical characteristics of patients tested for serum IgG4 because of suspecting IgG4-RD for a better understanding of the specific disorder. ....

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Animal study suggests intranasal COVID vaccine delivery more efficient than intramuscular

In a recent study published in the journal PNAS, researchers demonstrated higher comparative efficacy of the intranasal (IN) route of coronavirus disease 2019 (COVID-19) vaccine administration versus intramuscular route in mice. ....

United States , European Union , Serum Igg , Coronavirus Disease Covid 19 , Ngiotensin Converting Enzyme 2 , Covid 19 , Interferon Gamma , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Vaccinia Virus ,

Characterization of immune responses in fully vaccinated individuals following breakthrough infection with the SARS-CoV-2 delta variant

Characterization of immune responses in fully vaccinated individuals following breakthrough infection with the SARS-CoV-2 delta variant
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