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Young Adults Develop Rare Complication After COVID Vaccine: Study

Young Adults Develop Rare Complication After COVID Vaccine: Study
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United statesAmos hostetterAdrienne randolphDavid waltBoris juelgLael yonkerQuanterix corporationHuman developmentNational institute of diabetesNational institute of allergyNational institutes of healthChleck family foundationBrigham department of pathologyNational institute of child healthBlood instituteNational heart

Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates

Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates
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United kingdomUnited statesSanofi pasteurLuminex microplexJackson immunoresearchKit alpha diagnostics internationalBioqual incNational institute of allergyRnazol bd column kits molecular research centerRagon instituteTreestar incEuropean unionSeromyx systems incScripps research instituteVaccine research centerInfections research resources repository

Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women

This figure presents serum binding and functional antibody responses following COVID-19 vaccination and SARS-CoV-2 infection among women 45 years or younger. A and B, Each panel compares vaccine antibody responses at 2 through 8 weeks after the second dose to nonpregnant and pregnant women who were unvaccinated and infected. Thirteen women (7 nonpregnant, 4 pregnant, and 2 lactating) who had baseline samples collected within 7 days of their first vaccine dose were selected based on the earliest sample availability and were analyzed as a negative assay control. C, D, and E, Systems serology was used to quantify spike-specific antibody–dependent neutrophil phagocytosis (ADNP), antibody–dependent complement deposition (ADCD), and antibody–dependent monocyte cellular phagocytosis (ADCP).

United kingdomUnited statesMassachusetts institute of technologySouth africaPuro luc addgeneApraku bondzieCytofix cytopermDanh barouchGlo luciferase assay promega corpBurroughs wellcome fundRagon instituteBeth israel deaconess medical centerHarvard catalyst clinical research centerMelinda gates foundationRagon institute of massachusettsTraining program