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Blue Hill voters approve all ballot measures - The Ellsworth American


Blue Hill voters approve all ballot measures
BLUE HILL Voters here on April 20 elected a selectman and two School Board members and approved all 16 other ballot articles.
Article 7 asked voters if the town should raise $106,000 from property tax for additional tuition payments to George Stevens Academy. The academy was asking for an additional $1,000 per student above the state-set tuition rate. Both the Board of Selectmen and Budget Committee recommended a “no” vote, but voters said yes, approving the measure 277-200.
Voters also favored (345-131) expanding the Board of Selectmen from three members to five. The change will become effective at the 2022 annual Town Meeting, when an additional selectman will be elected to a two-year term and another to a three-year term. Also starting with the 2022 annual meeting, the position of road commissioner will transition from an elected to an appointed role. Voters approved that article 278-196. Compensation for selectmen, ....

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Individual receptors caught in the act of coupling


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NEW YORK, NY A new imaging technique developed by scientists at Columbia University Vagelos College of Physicians and Surgeons and St. Jude Children s Research Hospital captures movies of receptors on the surface of living cells in unprecedented detail and could pave the way to a trove of new drugs. 
The researchers used the technique to zoom in on individual receptor proteins on the surface of living cells to determine if the receptors work solo or come together to work as pairs. This work appeared in the April issue of 
Nature Methods.
If two different receptors come together to form a dimer with distinctive function and pharmacology, this might allow for a new generation of drugs with greater specificity and reduced side effects, says Jonathan Javitch, MD, PhD, the Lieber Professor of Experimental Therapeutics in Psychiatry at VP&S.   ....

Jonathana Javitch , Scott Blanchard , Avikk Pati , Scottc Blanchard , Daniels Terry , Michaeld Holsey , Wesleyb Asher , Kaleeckalg Harikumar Mayo , Weill Cornell , Zhou Weill Cornell , Laurencej Miller Mayo , Jonathan Javitch , Grantt Gilmore University Of Akron , Adamw Smith University Of Akron , Meganj Kaliszewski University Of Akron , Us National Institutes Of Health , National Science Foundation , Lieber Center , Behavior Research Foundation , Mitchelld Mccauley University Of Akron , Schizophrenia Research , Scholars Program , Queensborough Community College , Jude Children Research Hospital , Hope For Depression Research Foundation , Alekhya Govindaraju New York State Psychiatric Institute ,

Individual Receptors Caught in Act of Coupling


Columbia University Irving Medical Center
A new imaging technique developed by scientists at Columbia University Vagelos College of Physicians and Surgeons and St. Jude Children’s Research Hospital captures movies of receptors on the surface of living cells in unprecedented detail and could pave the way to a trove of new drugs.
The researchers used the technique to zoom in on individual receptor proteins on the surface of living cells to determine if the receptors work solo or come together to work as pairs. This work appeared in the April issue of Nature Methods.
“If two different receptors come together to form a dimer with distinctive function and pharmacology, this might allow for a new generation of drugs with greater specificity and reduced side effects.” ....

Jonathana Javitch , Scott Blanchard , Avikk Pati , Scottc Blanchard , Daniels Terry , Michaeld Holsey , Wesleyb Asher , Kaleeckalg Harikumar Mayo , Weill Cornell , Zhou Weill Cornell , Laurencej Miller Mayo , Jonathan Javitch , Grantt Gilmore University Of Akron , Adamw Smith University Of Akron , Meganj Kaliszewski University Of Akron , Us National Institutes Of Health , National Science Foundation , Lieber Center , Behavior Research Foundation , Mitchelld Mccauley University Of Akron , Schizophrenia Research , Scholars Program , Queensborough Community College , Jude Children Research Hospital , Hope For Depression Research Foundation , Alekhya Govindaraju New York State Psychiatric Institute ,

Taxpayers footed Pa.'s bill for election lawsuits. Costs went into the millions


Taxpayers footed Pa.’s bill for election lawsuits. Costs went into the millions
Updated 1:51 PM;
Today 1:17 PM
Rep. Mike Kelly, R-Pa., looks on in the House Chamber after they reconvened for arguments over the objection of certifying Arizona’s Electoral College votes in November’s election, at the Capitol in Washington, Wednesday, Jan. 6, 2021. Six weeks earlier, Kelly, an ally of President Trump, had filed a lawsuit that, had it been successful, would have canceled the legally cast votes of more than 2 million Pennsylvanians. (Caroline Brehman / Pool via AP Photo)
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By Julia Agos | WITF
Two weeks after the 2020 presidential election was called for Democrat Joe Biden, and as President Donald Trump sought to overturn the results, Pennsylvania Republican U.S. Sen. Pat Toomey issued a statement accepting Biden’s win. ....

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