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RNA exosome key for B cell development

RNA exosome key for B cell development
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United States , Tracey Wright , Kun Yang , Meghanan Sathe , Jyothsna Gattineni , Jie Han , Williamp Clements Jr , Nan Yan , Christian Wysocki , Jenniferg Gill , Burroughs Wellcome Fund , National Institutes Of Health , Haroldc Simmons Comprehensive Cancer Center , Children Medical Center Dallas , Columbia University , National Academy Of Medicine , National Academy Of Sciences , Scholar In Medical Research , Ut Southwestern Medical Center , University Of Washington , Department Of Immunology , Howard Hughes Medical Institute Investigators , Science Immunology , Comprehensive Cancer , Primary Immunodeficiency Clinic , Medical Center Dallas ,

Researchers find immune component to rare neurodegenerative disease

Researchers find immune component to rare neurodegenerative disease
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United States , Paulj Thomas , Michael Brown , Kun Yang , Louisa Beecherl Jr , Williamp Clements Jr , Wa Monty Moncrief , Nan Yan , Xintao Tu , Jianjun Wu , Joseph Goldstein , Ara Parseghian Medical Research Foundation , Scholar In Medical Research , Burroughs Wellcome Fund , National Institutes Of Health , Research Institute Of Texas , Arteriosclerosis Research , Biomedical Research , Nobel Prize , Ting Chu , Brain Microscopy , Proteomics Core , Live Cell Imaging Core , Transgenic Core , National Institutes , Cancer Prevention ,

How human cells and pathogenic shigella engage in battle

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IMAGE: A new study finds that gasdermin B (GSDMB) pokes holes in bacterial membranes containing cardiolipin as a novel immune defense strategy. Shown are pictures of GSDMB pores embedded in synthetic.
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Credit: Justin M. Hansen
DALLAS - May 21, 2021 - One member of a large protein family that is known to stop the spread of bacterial infections by prompting infected human cells to self-destruct appears to kill the infectious bacteria instead, a new study led by UT Southwestern scientists shows. However, some bacteria have their own mechanism to thwart this attack, nullifying the deadly protein by tagging it for destruction. ....

United States , Lorraine Sulkin Schein , Williamp Clements Jr , Davidb Heisler , Qi Wu , Li Shu Zhang , Justinm Hansen , Simons Foundation Faculty Scholars Program , Scholar In Medical Research , Burroughs Wellcome Fund , National Institutes Of Health , Haroldc Simmons Comprehensive Cancer Center , Howard Hughes Medical Institute , Welch Foundation , Comprehensive Cancer , National Institutes , Medical Research , ஒன்றுபட்டது மாநிலங்களில் , குய் வு , லி ஷு ஜாங் , சிமன்கள் அடித்தளம் ஆசிரிய அறிஞர்கள் ப்ரோக்ர்யாம் , அறிஞர் இல் மருத்துவ ஆராய்ச்சி , பரோக்கள் வெல்கம் நிதி , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , ஹோவர்ட் ஹக்ஸ் மருத்துவ நிறுவனம் , வெல்ச் அடித்தளம் ,