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Bacterial proteins shed light on antiviral immunit

A unique collaboration between two UT Southwestern Medical Center labs - one that studies bacteria and another that studies viruses - has identified two im

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UT Southwestern scientists discover antiviral immune pathway

By focusing on a poxvirus protein, a team led by UT Southwestern Medical Center scientists has discovered an antiviral immune pathway that broadly fights a wide

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UT Southwestern scientists discover antiviral immune pathway

By focusing on a poxvirus protein, a team led by UT Southwestern Medical Center scientists has discovered an antiviral immune pathway that broadly fights a wide

Dallas
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How human cells and pathogenic shigella engage in battle

 E-Mail IMAGE: A new study finds that gasdermin B (GSDMB) pokes holes in bacterial membranes containing cardiolipin as a novel immune defense strategy. Shown are pictures of GSDMB pores embedded in synthetic. view more  Credit: Justin M. Hansen DALLAS - May 21, 2021 - One member of a large protein family that is known to stop the spread of bacterial infections by prompting infected human cells to self-destruct appears to kill the infectious bacteria instead, a new study led by UT Southwestern scientists shows. However, some bacteria have their own mechanism to thwart this attack, nullifying the deadly protein by tagging it for destruction.

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