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Research identifies mechanisms for selective multiple sclerosis treatment strategy

The Wistar Institute s Paul M. Lieberman, Ph.D., and lab team led by senior staff scientist and first author Samantha Soldan, Ph.D., have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS). The group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis. ....

Samantha Soldan , Steven Jacobson , Samanthas Soldan , National Institute Of Neurological Disorders , Neuroimmunology Branch , Wistar Institute Paulm Lieberman , Nature Microbiology , Wistar Institute , National Institute , Neurological Disorders ,

Understanding the link between EBV-infected B cells and multiple sclerosis

The Wistar Institute's Paul M. Lieberman, Ph.D., and lab team led by senior staff scientist and first author, Samantha Soldan, Ph.D., have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis. ....

Paulm Lieberman , Steven Jacobson , Samantha Soldan , National Institute Of Neurological Disorders , Neuroimmunology Branch , Wistar Institute , Wistar Institute Paulm Lieberman , Nature Microbiology , National Institute , Neurological Disorders ,