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IS IT TRUE APRIL !0, 2023

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Vanderburgh County , United States , James Raben , Jude Children Research Hospital , Health Milwaukee , Evansville Sports Corp , Vanderburgh County Council , County Observer Comment , City County Observer , Evansville Sports , County Council , Tom Shelter , Revenue Bonds , Law Enforcement , Weekly Birthday , Hot Jobs , Mayo Clinic , Jude Children , Research Hospital Memphis ,

Kosminis turizmas jau čia pat: metų pabaigoje suplanuotas pirmasis skrydis – kas bus pirmieji turistai?

Kosminis turizmas jau čia pat: metų pabaigoje suplanuotas pirmasis skrydis – kas bus pirmieji turistai?
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Elon Uswho , Research Hospital Memphis , Thaddeus Hospital , ஆராய்ச்சி மருத்துவமனை மெம்பிஸ் ,

Understanding Topotecan's Cancer Inhibiting Power

Topotecan, a cancer inhibitor, interacts with an important protein (TopoIB), causing a (cancer) cell to malfunction. The TopoIB protein is responsible for the removal of loops from DNA, which arise amongst other things during cell division.
The TopoIB protein binds to the DNA molecule, clamps around it and cuts one of the two DNA strands, after which it allows it to unwind and finally joins the broken ends together.
Until now it has been supposed that topotecan only causes the TopoIB protein to reside longer than normal on the DNA molecule, disturbing the cell division and damaging the (cancer) cell. But the researchers at the University of Delft have now discovered that adding topotecan also dramatically impedes the unwinding and that DNA loops accumulate as a result. The accumulation of these DNA loops forms the basis for an alternative mechanism, and could help in the development of better cancer medicine. ....

Nynke Dekker , Komaraiah Palle , Daniel Koster , Daniela Koster , Jude Children Research Hospital Memphis United States , University Of Delft , Kavli Institute Of Nanoscience Delft , Elisa Bot , Molecular Biophysics , Kavli Institute , Nanoscience Delft , Jude Children , Research Hospital Memphis , United States , Dmary Ann Bjornsti , டேனியல் கோஸ்டர் , டேனீலா கோஸ்டர் , ஜூட் குழந்தைகள் ஆராய்ச்சி மருத்துவமனை மெம்பிஸ் ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் ஆஃப் டெல்ஃப்ட் , கவிளி நிறுவனம் ஆஃப் நானோ அறிவியல் டெல்ஃப்ட் , எலிசா போட் , மூலக்கூறு உயிர் இயற்பியல் , கவிளி நிறுவனம் , நானோ அறிவியல் டெல்ஃப்ட் , ஜூட் குழந்தைகள் , ஆராய்ச்சி மருத்துவமனை மெம்பிஸ் ,