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Cureus | A Systematic Review of Apoptosis in Correlation With Cancer: Should Apoptosis Be the Ultimate Target for Cancer Treatment?

Targeting apoptosis in cancer therapy has become increasingly popular, and there has been an increasing debate on whether apoptosis should be one of the main targets of therapy in cancer management. This study demonstrates the definition of apoptosis, the signaling pathways, and the pathogenesis behind it. We also show the correlation between apoptosis and cancer and how cancer can evade apoptosis to develop resistance to therapy. In addition, we illustrate the efficacy of adding pro-apoptotic therapy to conventional radio-chemotherapy cancer treatment.

A systematic review was conducted using PubMed, PubMed Central (PMC), and ResearchGate, including papers written in English, focusing on adult and geriatric populations, in literature reviews, systematic reviews, and randomized controlled trials published in the last 25 years with relevance to the question.

Based on the findings of this review, we conclude that apoptosis is a very sophisticated programmed cellular deat ....

Robert Horvitz , Development Of Multiple Drug Resistance , Pubmed Central , Reporting Items , Systematic Reviews , Medical Subject Headings , Multiple Systematic Reviews , Narrative Review Articles , Randomized Controlled Trials , Preferred Reporting Items , Correlation With Cancer , Multiple Drug Resistance ,

Acute illness increases cortisol levels in children and adolescents

A new study reports that in children and adolescents without glucocorticoid deficiency, circulating cortisol levels were higher during acute illnesses. ....

Kock Shutterstock , Cochrane Library , Network Openstudy , Cortisol Levels During Acute Illnesses , Image Credit , Reporting Items , Systematic Reviews , Healthcare Databases Advanced Search , Cochrane Database ,

36-fold higher estimate of deaths attributable to red meat intake in GBD 2019: is this reliable?

36-fold higher estimate of deaths attributable to red meat intake in GBD 2019: is this reliable?
thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.

South Korea , United States , United Kingdom , Brussels Capital Region , Bruxelles Capitale , Region Flamande , J Clin Nutr , Food Strategy Committee , Flemish Strategic Advisory Council For Agriculture , Belgian Society For Food Microbiology , Foods Of The Ministry , Horizon Europe Cancer Mission Assembly , Scientific Advisory Committee Of Foundation Earth , Belgian Nutrition Society , Health Coalition , Glob Health , Sustainable Development Goals , World Food Programme , Transparent Health Estimates , National Food Strategy , Institute Danone Belgium , Transparent Health Estimates Reporting , American Institute For Cancer Research , United Kingdom National Food Strategy , Elsevier Ltd , World Cancer Research Fund ,

SEC Proposes Updates To Form PF - Finance and Banking

On January 26, 2022, the SEC issued a release (the "Release") proposing amendments to Form PF (the "Proposal"). The Proposal includes: (i) new current reporting requirements for large hedge fund advisers. ....

Current Reporting Requirements For Large Hedge Fund , Large Liquidity Fund Adviser , Liquidity Fund , Events For Large Hedge Fund Advisers , Current Reporting Requirements , Large Hedge Fund , Private Equity , Private Fund Reporting , Unencumbered Cash , Large Private Equity Adviser , Reporting Items , Sec Proposes Updates To Form Pf , Corporate Commercial Law , Corporate And Company Law , Finance And Banking , Financial Services ,

Racialised people in clinical guideline panels

Racialised people in clinical guideline panels
thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.

United States , United Kingdom , Maytree Foundation , St Michael Hospital Foundation , Metcalf Foundation , Elsevier Ltd , Canadian Institute For Health Information , Atkinson Foundation , Public Health , Research Ethics Board Of Unity Health Toronto , Public Health Agency Of Canada , Canadian Institutes For Health Research , Humanities Research Council , Canadian Medical Association Journal , British Medical Journal , Medical Journal , Research Ethics Board , Unity Health , Reporting Items , Intern Med , Canadian Institutes , Health Research , Hospital Foundation , Public Health Agency , Social Science , Cancer Care ,