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A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery ....
STONY BROOK, NY, June 29, 2022 – A new biomedical research tool that enables scientists to measure hundreds of functional proteins in a single cell could offer new insights into cell machinery. Led by Jun Wang, Associate Professor of Biomedical Engineering at Stony Brook University, this microchip assay called the single-cell cyclic multiplex in situ tagging (CycMIST) technology – may help to advance fields such as molecular diagnostics and drug discovery. Details about the cyclic microchip assay method are published in Nature Communications. While newer technologies of single-cell omics (ie, genomics, transcriptomics, etc.) are revolutionizing the study of complex biological and cellular systems and scientists can analyze genome-wide sequences of individual cells, these technologies do not apply to proteins because they are not amplifiable like DNAs. Thus, protein analysis in single cells has not reached large-scale experimentation. Because proteins represent cell functions a ....
A study of 1,280 patients treated and monitored at the Stony Brook World Trade Center Health and Wellness Program who also contracted Covid-19 reveals that the responders who have suffered from chronic conditions from WTC exposures and the experience of the 911 tragedy appear to have more infection severity and long-term sequelae than responders who do not have chronic diseases resulting from WTC exposures. ....