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Proteins modified in lungs offer clues to biological functions of bromine

Researchers at the Center for Research on Redox Processes in Biomedicine (Redoxome) in Brazil have identified extracellular matrix proteins modified by the action of hypobromous acid in normal and fibrotic lung tissues, suggesting a possible physiological role for protein bromination. This is the first study to identify brominated proteins in pulmonary fibrosis and non-fibrotic lung tissue. ....

Flavia Meotti , Litiele Cezar Cruz , Research On Redox Processes In Biomedicine Redoxome , Redox Biology , Redox Processes ,

Research Sheds Light on Cellular Energy Metabolism Regulation

Research Sheds Light on Cellular Energy Metabolism Regulation
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

United Kingdom , Miranda Ramos , Viktor Korolchuk , Alicia Kowaltowski , Newcastle University , Research On Redox Processes In Biomedicine Redoxome , Dissemination Center , Paulo Institute Of Chemistry , Faseb Journal , Redox Processes , Vitor De Miranda Ramos ,

Study elucidates how energy metabolism is regulated at cellular level

Study elucidates how energy metabolism is regulated at cellular level
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

United Kingdom , Viktor Korolchuk , Alicia Kowaltowski , Miranda Ramos , Vitorm Ramos , Newcastle University , Dissemination Center , Research On Redox Processes In Biomedicine Redoxome , Paulo Institute Of Chemistry , Vitor De Miranda Ramos , Vitor De Miranda , Redox Processes ,

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases
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Britto Chaves Filho , Adrianob Chaves Filho , Sayuri Miyamoto , Dissemination Center , Research On Redox Processes In Biomedicine Redoxoma , Paulo Chemistry Institute , Free Radical Biology , Redox Processes , Chemistry Institute , Adriano De Britto Chaves Filho ,

Study helps understand why kids of obese mothers may be susceptible to metabolic diseases


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IMAGE: Image of a mitofusin-2 deficient egg shows mitochondria [stained green] to be fewer, more aggregated, and swollen than in controls
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Credit: Marcos Chiaratti
A Brazilian study published in the journal
Molecular Human Reproduction helps understand why obese mothers tend to have children with a propensity to develop metabolic disease during their lifetime, as suggested by previous research.
According to the authors, transgenerational transmission of metabolic diseases may be associated with Mfn2 deficiency in the mother s oocytes (immature eggs). Mfn2 refers to mitofusin-2, a protein involved in the regulation of vascular smooth muscle cell proliferation. It is normally found in the outer membrane of mitochondria, the organelles that supply cells with energy. A deficiency leads to mitochondrial swelling and dysfunction, as well as altering the expression of almost 1,000 genes in female gametes. ....

Bruna Garcia , Carlos Ufscar , Alicia Kowaltowski , Marcos Chiaratti , Dissemination Centers Ridcs , Comorbidities Research Center , Paulo Research Foundation , Research On Redox Processes In Biomedicine Redoxome , Ufscar Center , Paulo Chemistry Institute , Health Sciences , Molecular Human Reproduction , Federal University , Redox Processes , Dissemination Centers , Chemistry Institute , புருனா கார்சியா , பாலொ ஆராய்ச்சி அடித்தளம் , பாலொ வேதியியல் நிறுவனம் , ஆரோக்கியம் அறிவியல் , மூலக்கூறு மனிதன் இனப்பெருக்கம் , கூட்டாட்சியின் பல்கலைக்கழகம் , ரெடாக்ஸ் ப்ரோஸெஸஸ் , பரப்புதல் மையங்கள் , வேதியியல் நிறுவனம் ,